828247-64-9

Basic information

• Product Name: (+)-Amlodipine besylate
• Synonyms: (+)-Amlodipine besylate
• CAS NO: 828247-64-9
• Molecular Weight: 567.06
• Mol File: 828247-64-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-Amlodipine besylate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Amlodipine besylate(828247-64-9)
• EPA Substance Registry System: (+)-Amlodipine besylate(828247-64-9)

Safety Data

• Hazardous Substances Data: 828247-64-9(Hazardous Substances Data)

Upstream product

• 111470-99-6 amlodipine besylate 
• 98-11-3 benzenesulfonic acid 

Relevant articles and documents

Combined use of ionic liquid and hydroxypropyl-β-cyclodextrin for the enantioseparation of ten drugs by capillary electrophoresis

In the present study, hydroxypropyl-β-cyclodextrin and an ionic liquid (1-ethyl-3-methylimidazolium-l-lactate) were used as additives in capillary electrophoresis for the enantioseparation of 10 analytes, including ofloxacin, propranolol hydrochloride, dioxopromethazine hydrochloride, isoprenaline hydrochloride, chlorpheniramine maleate, liarozole, tropicamide, amlodipine benzenesulfonate, brompheniramine maleate, and homatropine methylbromide. The effects of ionic liquid concentrations, salt effect, cations, and anions of ionic liquids on enantioseparation were investigated and the results proved that there was a synergistic effect between hydroxypropyl-β-cyclodextrin and the ionic liquid, and the cationic part of the ionic liquid played an important role in the increased resolution. With the developed dual system, all the enantiomers of 10 analytes were well separated in resolutions of 5.35, 1.76, 1.85, 2.48, 2.88, 1.43, 5.45, 4.35, 2.76, and 2.98, respectively. In addition, the proposed method was applied to the determination of the enantiomeric purity of S-ofloxacin after validation of the method in terms of selectivity, repeatability, linearity range, accuracy, precision, limit of detection (LOD), and limit of quality (LOQ). Chirality 25:409-414, 2013.