828272-16-8

Basic information

• Product Name: 2-Oxazolidinone,5-(hydroxymethyl)-3-methyl-4-phenyl-,(4R,5S)-rel-(9CI)
• Synonyms: 2-Oxazolidinone,5-(hydroxymethyl)-3-methyl-4-phenyl-,(4R,5S)-rel-(9CI)
• CAS NO: 828272-16-8
• Molecular Formula: C11H13NO3
• Molecular Weight: 207.22582
• Product Categories: METHYL
• Mol File: 828272-16-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Oxazolidinone,5-(hydroxymethyl)-3-methyl-4-phenyl-,(4R,5S)-rel-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone,5-(hydroxymethyl)-3-methyl-4-phenyl-,(4R,5S)-rel-(9CI)(828272-16-8)
• EPA Substance Registry System: 2-Oxazolidinone,5-(hydroxymethyl)-3-methyl-4-phenyl-,(4R,5S)-rel-(9CI)(828272-16-8)

Safety Data

• Hazardous Substances Data: 828272-16-8(Hazardous Substances Data)

Upstream product

• 165683-81-8 (2S,3S)-3-((tert-butoxycarbonyl)amino)-3-phenyl-1,2-propanediol 
• 75-44-5 phosgene 
• 873396-25-9 3-methylamino-3-phenyl-1,2-propanediol 

Relevant articles and documents

Novel examples of the N-methyl effect on cyclisations of N-Boc derivatives of amino alcohols. A theoretical study

New examples of the N-methyl effect on the cyclisation of N-tert-butoxycarbonyl derivatives of amino alcohols are reported. Ab initio studies for the displacement step with formation of the five-membered heterocycle indicate that the increase of the nucleophile character of the carbonyl oxygen of the carbamate group with the N-methyl substitution is responsible for the acceleration of the cyclisation step. Graphical Abstract