82946-72-3

Basic information

• Product Name: 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE
• Synonyms: 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE
• CAS NO: 82946-72-3
• Molecular Formula: C₁₂H₁₅NO
• Molecular Weight: 0
• Mol File: 82946-72-3.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE(82946-72-3)
• EPA Substance Registry System: 4,5-DIHYDRO-4,4-DIMETHYL-2-M-TOLYLOXAZOLE(82946-72-3)

Safety Data

• Hazardous Substances Data: 82946-72-3(Hazardous Substances Data)

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 500131-50-0 N,N-diethyl-α,α-difluoro-(meta-methylbenzyl)amine 
• 620-23-5 m-tolyl aldehyde 
• 1711-06-4 3-Methylbenzoyl chloride 
• 99-04-7 m-Toluic acid 
• 30093-99-3 4,4-dimethyl-2-oxazoline 
• 625-95-6 3-Iodotoluene 
• 591-17-3 meta-bromotoluene 
• 535-80-8 3-chlorobenzoate 
• 701923-86-6 3-Chloro-N-(2-hydroxy-1,1-dimethyl-ethyl)-benzamide 
• 618-46-2 m-Chlorobenzoyl chloride 
• 134-62-3 N,N-Diethyl-3-methylbenzamide 
• 917-54-4 methyllithium 
• 80762-49-8 2-(m-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole 

Downstream Products

• 99-36-5 1-methoxycarbonyl-3-methylbenzene 
• 1386451-20-2 4,4-dimethyl-2-{5-methyl-2-[bis(trimethylsiloxy)(methyl)silyl]phenyl}-4,5-dihydrooxazole 

Relevant articles and documents

Nickel-catalyzed reductive defunctionalization of esters in the absence of an external reductant: Activation of C-O bonds

The nickel-catalyzed reductive cleavage of esters in the absence of an external reductant, which involves the cleavage of an inert acyl C-O bond in O-Alkyl esters is reported. Various groups, such as N-containing heterocycles, esters, amides, and even arene rings can function as a directing group.

Photoinduced Copper-Catalyzed C-H Arylation at Room Temperature

Room-temperature azole C-H arylations were accomplished with inexpensive copper(I) compounds by means of photoinduced catalysis. The expedient copper catalysis set the stage for site-selective C-H arylations of non-aromatic oxazolines under mild reaction conditions, and provides step-economical access to the alkaloid natural products balsoxin and texamine. Copper light: Room-temperature C-H arylations of heteroarenes were accomplished with inexpensive copper compounds by photoinduced catalysis. The expedient copper catalysis leads to site-selective C-H arylations of non-aromatic oxazolines under mild reaction conditions, and provides step-economical access to the alkaloid natural products balsoxin and texamine.

C-H bond arylations and benzylations on oxazol(in)es with a palladium catalyst of a secondary phosphine oxide

An air-stable, well-defined palladium complex derived from secondary phosphine oxide (SPO) (1-Ad)2P(O)H enabled efficient C-H bond functionalizations with ample scope, which set the stage for direct arylations and benzylations of (benz)oxazoles, as well as unprecedented palladium-catalyzed C-H bond arylations on nonaromatic oxazolines.