82948-92-3

Basic information

• Product Name: [des-tyr¹]-leucine enkephalinamide
• Synonyms: [des-tyr¹]-leucine enkephalinamide
• CAS NO: 82948-92-3
• Molecular Weight: 391.47
• Mol File: 82948-92-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [des-tyr¹]-leucine enkephalinamide(CAS DataBase Reference)
• NIST Chemistry Reference: [des-tyr¹]-leucine enkephalinamide(82948-92-3)
• EPA Substance Registry System: [des-tyr¹]-leucine enkephalinamide(82948-92-3)

Safety Data

• Hazardous Substances Data: 82948-92-3(Hazardous Substances Data)

Upstream product

• 75286-46-3 amide of N-t-butyloxycarbonylglycylglycyl-L-phenylalanyl-L-leucine 
• 74257-73-1 tert-butyl ((S)-1-(((S)-1-amino-4-methyl-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 93200-07-8 Boc-Gly-Phe-Leu-NH₂ 
• 81638-86-0 (S)-2-((S)-2-amino-3-phenylpropanamido)-4-methylpentanamide hydrochloride 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 71591-20-3 H-Gly-Phe-Leu-NH₂ 
• 38678-59-0 L-Phe-L-Leu-NH₂ 
• 35909-92-3 N-carbobenzoxy-L-phenylalanine methyl ester 
• 69193-15-3 N-(benzyloxycarbonyl)-glycyl-L-phenylalanyl-L-leucine amide 
• 69193-13-1 Cbz-L-Phe-L-Leu-NH₂ 
• 687-51-4 H-L-Leu-NH₂ 
• 169676-30-6 Z-Gly-Gly-L-Phe-OCH₂CF₃ 
• 10466-61-2 (2S)-amino-4-methylpentanamide hydrochloride 
• 15027-03-9 Z-Gly-Gly-L-Phe-OMe 

Downstream Products

• 81638-88-2 amide of N-t-butyloxycarbonyl-O-benzyl-L-tyrosylglycylglycyl-L-phenylalanyl-L-leucine 
• 79396-86-4 Boc-L-Tyr-Gly-Gly-L-Phe-L-Leu-NH₂ 
• 75286-46-3 amide of N-t-butyloxycarbonylglycylglycyl-L-phenylalanyl-L-leucine 
• 1313481-74-1 Boc-Tyr(tBu)-Gly-Gly-Phe-Leu-NH₂ 
• 81638-87-1 hydrochloride of amide of glycylglycyl-L-phenylalanyl-L-leucine 
• 217792-91-1 2,2-dimethyl-thiopropionic acid S-(2-{[4-(2-amino-2-{[({[1-(1-carbamoyl-3-methyl-butylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamoyl}-ethyl)-phenoxy]-[2-(2,2-dimethyl-propionylsulfanyl)-ethoxy]-phosphoryloxy}-ethyl) ester 
• 71591-21-4 Z-Tyr-Gly-Gly-Phe-Leu-NH₂ 

Relevant articles and documents

Peptide synthesis 'in water' by a solution-phase method using water-dispersible nanoparticle Boc-amino acid

Regulatory pressure has compelled the chemical manufacturing industry to reduce the use of organic solvents in synthetic chemistry, and there is currently a strong focus on replacing these solvents with water. Here, we describe an efficient in-water solution-phase peptide synthesis method using Boc-amino acids. It is based on a coupling reaction utilizing suspended water-dispersible nanoparticle reactants. Using this method, peptides were obtained in good yield and with high purity.

Phosphopeptide prodrug bearing an S-acyl-2-thioethyl enzyme-labile phosphate protection

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