83004-15-3

Basic information

• Product Name: 4-(BROMOMETHYL)-2-CHLOROPYRIDINE
• Synonyms: 4-(BROMOMETHYL)-2-CHLOROPYRIDINE;Pyridine, 4-(bromomethyl)-2-chloro-
• CAS NO: 83004-15-3
• Molecular Formula: C₆H₅BrClN
• Molecular Weight: 206.47
• Mol File: 83004-15-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 264.4 °C at 760 mmHg
• Flash Point: 113.7 °C
• Appearance: /
• Density: 1.663 g/cm³
• Vapor Pressure: 0.0159mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 4-(BROMOMETHYL)-2-CHLOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(BROMOMETHYL)-2-CHLOROPYRIDINE(83004-15-3)
• EPA Substance Registry System: 4-(BROMOMETHYL)-2-CHLOROPYRIDINE(83004-15-3)

Safety Data

• Hazardous Substances Data: 83004-15-3(Hazardous Substances Data)

Usage

General Description

4-(bromomethyl)-2-chloropyridine is a chemical compound with the molecular formula C6H5BrClN. It is a halogenated pyridine derivative, containing both bromine and chlorine atoms. 4-(BROMOMETHYL)-2-CHLOROPYRIDINE is used as a building block in organic synthesis for the preparation of various pharmaceuticals and agrochemicals. It is also used as an intermediate in the production of other chemicals and in research laboratories for its role as a starting material in the development of new compounds. 4-(bromomethyl)-2-chloropyridine is classified as a moderately hazardous chemical and should be handled and used with appropriate safety precautions.

InChI:InChI=1/C6H5BrClN/c7-4-5-1-2-9-6(8)3-5/h1-3H,4H2

Upstream product

• 3678-62-4 2-chloro-4-picoline 
• 6313-54-8 2-chloroisonicotinic acid, 
• 100704-10-7 (2-chloropyridin-4-yl)methanol 
• 58481-11-1 methyl 2-chloroisonicotinate 

Downstream Products

• 950889-33-5 (2R,3R)-1-[4-(2-Chloro-pyridin-4-ylmethoxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid tert-butyl ester 
• 945257-67-0 1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)thio]phenyl}imidazolidine-2,4-dione 
• 1239355-10-2 N-[(1R)-1-({[(2-chloropyridin-4-yl)methyl]oxy}methyl)-2-(4-methylpiperazin-1-yl)-2-oxoethyl]-2-{[2-chloro-4-(trifluoromethyl)phenyl]oxy}pyridine-3-carboxamide 
• 1258864-81-1 (E)-5-chloro-1'-(3-(4-chlorophenyl)allyl)-1-((2-chloropyridin-4-yl)methyl)spiro[indoline-3,4'-piperidin]-2-one 
• 1155195-15-5 3-chloro-N-((2-chloropyridin-4-yl)methyl)aniline 

Relevant articles and documents

One-pot directed alkylation/deprotection strategy for the synthesis of substituted pyrrole[3,4-d]pyridazinones

In the course of a structure-activity relationship study of pyrrole[3,4-d]pyridazinones, we optimized conditions for a one-pot directed lithiation/alkylation reaction that also promoted in situ cleavage of a tert-butoxycarbonyl (Boc) protecting group on t

FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor.(Formula I) (I)

LABELLED CHROMONE DERIVATIVES

The present invention relates to compounds having selective binding for MAO-B as compared with MAO-A. The invention also provides radioactive versions of these compounds, and precursor compounds for the synthesis of these radioactive compounds. The radioa