83023-81-8

Basic information

• Product Name: Propanoic acid, 2-hydroxy-3-(phenylthio)-, (R)-
• CAS NO: 83023-81-8
• Molecular Formula: C9H10O3S
• Molecular Weight: 198.243
• Mol File: 83023-81-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-hydroxy-3-(phenylthio)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-hydroxy-3-(phenylthio)-, (R)-(83023-81-8)
• EPA Substance Registry System: Propanoic acid, 2-hydroxy-3-(phenylthio)-, (R)-(83023-81-8)

Safety Data

• Hazardous Substances Data: 83023-81-8(Hazardous Substances Data)

Upstream product

• 111248-06-7 methyl 2-hydroxy-3-(phenylthio)-propionate 
• 82079-45-6 potassium de l'acide (S)-(-)-epoxy-2,3 propionique 
• 108-98-5 thiophenol 
• 111248-38-5 phenylthioacetaldehyde cyanohydrin acetate 
• 111248-41-0 2-(1-pyrrolidinyl)-3-phenylthiopropionitrile 
• 51877-54-4 potassium oxirane-2-carboxylate 

Downstream Products

• 1370639-66-9 C₁₅H₁₈O₃S 
• 140371-04-6 (R)-2-Hydroxy-3-(phenylsulphonyl)propanoic acid 
• 140663-05-4 (2S,5R)-5-Benzenesulfonylmethyl-2-cyclohexyl-[1,3]dioxolan-4-one 
• 128677-44-1 (2S,5S)-2-Cyclohexyl-5-phenylsulfanylmethyl-[1,3]dioxolan-4-one 
• 128677-44-1 (2S,5R)-2-Cyclohexyl-5-phenylsulfanylmethyl-[1,3]dioxolan-4-one 
• 128677-43-0 (2S,5S)-2-tert-Butyl-5-phenylsulfanylmethyl-[1,3]dioxolan-4-one 
• 128677-43-0 (2S,5R)-2-tert-Butyl-5-phenylsulfanylmethyl-[1,3]dioxolan-4-one 
• 111248-06-7 (R)-2-Hydroxy-3-phenylsulfanyl-propionic acid methyl ester 
• 111248-06-7 methyl 2-hydroxy-3-(phenylthio)-propionate 
• 82971-71-9 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-1-methoxycarbonyl-2-phenylsulfanyl-ethyl ester 
• 82971-70-8 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-1-methoxycarbonyl-2-phenylsulfanyl-ethyl ester 

Relevant articles and documents

Enantioselective, chromatography-free synthesis of β3-Amino acids with natural and unnatural side chains

β3-Amino acids are key components of some pharmaceuticals, excellent surrogates for metabolically labile α-amino acids, and building blocks for chiral heterocycles. Unfortunately they are not easily accessible in enantiomerically pure form, especially when possessing unnatural side chains. A flexible, chromatography-free process for the synthesis of enantiopure β3-amino acids possessing natural and unnatural side chains is described. The procedure uses inexpensive starting materials and reagents and offers a good alternative to the hazardous and expensive Arndt-Eistert homologation of enantiopure α-amino acids. Its utility has been demonstrated with the preparative scale synthesis of two valuable β3-amino acids possessing unnatural side chains.

Synthesis and Diels-Alder reactions of 2-alkyl-5-methylene-1,3-dioxolan-4-ones and 2-alkyl-3-acyl-5-methylene-1,3-oxazolidin-4-ones: Highly exo and diastereoface selective chiral ketene equivalents

Chiral dienophiles 1-3 undergo highly exo and diastereoface selective Diels-Alder reactions. The Diels-Alder reactions of 3 are also highly exo selective under Lewis acid catalyzed conditions.

Laboratory-Scale Enzymatic/Chemical Syntheses of D- and L-β-Chlorolactic Acid and D- and L-Potassium Glycidate

This paper describes preparations of D- (and L-) chlorolactic acids having enantiomeric excesses greater than 97percent by D- (and L-) lactate dehydrogenase catalyzed reduction of chloropyruvic acid with NADH.In syntheses carried out on 0.1-0.5 mol scales