83128-61-4

Basic information

• Product Name: 5-Brom-1-cyclohexyl-5-ethyl-barbitursaeure
• Synonyms: 5-Brom-1-cyclohexyl-5-ethyl-barbitursaeure
• CAS NO: 83128-61-4
• Molecular Weight: 317.183
• Mol File: 83128-61-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Brom-1-cyclohexyl-5-ethyl-barbitursaeure(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Brom-1-cyclohexyl-5-ethyl-barbitursaeure(83128-61-4)
• EPA Substance Registry System: 5-Brom-1-cyclohexyl-5-ethyl-barbitursaeure(83128-61-4)

Safety Data

• Hazardous Substances Data: 83128-61-4(Hazardous Substances Data)

Upstream product

• 837-32-1 1-cyclohexyl-5-ethyl-pyrimidine-2,4,6-trione 
• 133-13-1 ethyl diethyl malonate 
• 698-90-8 N'-cyclohexylurea 

Downstream Products

• 83128-82-9 (+)-1-Cyclohexyl-5-ethyl-5-pyrrolidino-barbitursaeure 
• 83128-82-9 (-)-1-Cyclohexyl-5-ethyl-5-pyrrolidino-barbitursaeure 
• 345932-03-8 (+/-)-1-Cyclohexyl-5-ethyl-5-pyrrolidino-barbitursaeure 
• 83128-75-0 (+)-1-Cyclohexyl-5-ethyl-5-piperidino-barbitursaeure 
• 83128-75-0 (-)-1-Cyclohexyl-5-ethyl-5-piperidino-barbitursaeure 
• 101693-71-4 (RS)-1-cyclohexyl-5-ethyl-5-(1-piperidinyl)-2,4,6(1H,3H,5H)-pyrimidinetrione 
• 83129-39-9 (+/-)-1-Cyclohexyl-5-ethyl-5-dimethylamino-barbitursaeure 
• 221679-72-7 5-Azido-1-cyclohexyl-5-ethylbarbituric acid 
• 221679-69-2 5-amino-1-cyclohexyl-5-ethylbarbituric acid 

Relevant articles and documents

A new one-pot synthesis of 5,5-disubstituted hydantoins from diethyl acetamidomalonates and ureas

A new one-pot synthesis of 5,5-disubstituted hydantoins 3 is reported. Diethyl 2-acetamido-2-alkylmalonates were found to react with substituted ureas in the presence of sodium ethoxide to produce the 5-alkyl-5- carbamoylhydantoins 3 a-e. The reaction involves a ring contraction of intermediate 5-aminobarbituric acids to the final hydantoin derivatives. The 5-aminobarbituric acids 2 d-f were prepared from azido derivatives 6 d-f. On treatment with sodium ethoxide, 2 d-f underwent the rearrangement to afford the hydantoins 3 d-f.