83150-77-0

Basic information

• Product Name: (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol
• Synonyms: (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol;(S)-α,α,4-Trimethyl-3-cyclohexene-1-methanethiol;Einecs 280-196-4
• CAS NO: 83150-77-0
• Molecular Formula: C10H18S
• Molecular Weight: 170.31492
• EINECS: 280-196-4
• Mol File: 83150-77-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 229.4°Cat760mmHg
• Flash Point: 90.7°C
• Appearance: /
• Density: 0.938g/cm³
• Vapor Pressure: 0.105mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol(83150-77-0)
• EPA Substance Registry System: (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol(83150-77-0)

Safety Data

• Hazardous Substances Data: 83150-77-0(Hazardous Substances Data)

Usage

General Description

(S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol is a chemical compound classified as a thiol, which is a type of organic compound containing a sulfhydryl group. It is commonly used in the fragrance industry as a component in perfumes and colognes due to its strong and distinct odor. (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol is also found in certain food items and is responsible for contributing to their characteristic smell and taste. With its unique and pungent aroma, (S)-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanethiol serves as a fragrant and flavoring agent in various consumer products. Additionally, it is an important building block in the synthesis of other chemicals and is used in the production of pharmaceuticals, dyes, and other industrial products.

InChI:InChI=1/C10H18S/c1-8-4-6-9(7-5-8)10(2,3)11/h4,9,11H,5-7H2,1-3H3/t9-/m1/s1

Upstream product

• 7785-26-4 (-)-α-pinene 
• 127-91-3 (1R,5R)-(+)-β-pinene 
• 83108-08-1 8,9-epthio-1-p-menthene 
• 133490-04-7 α-terpinyl thiocyanate 
• 7783-06-4 hydrogen sulfide 
• 138-86-3 limonene. 
• 586-62-9 Terpinolene 
• 10482-56-1 (-)-(S)-α-terpineol 
• 5989-27-5 D-limonene 
• 39864-10-3 α-terpinyl chloride 
• 98-55-5 terpineol 

Relevant articles and documents

Method for preparing 1-poxlene -8-thiol

The invention belongs to the technical field of fine chemistry, and provides a method for preparing 1-poxlene-8-thiol, wherein a-terpineol is used as a raw material, and the a-terpineol reacts with athioreagent to obtain the 1-poxlene -8-thiol, the method comprises the following steps: dissolving the a-terpineol in an organic solvent; adding the thioreagent in batches to carry out a thioreaction;the system after reaction is cooled to room temperature, the solvent is removed through rotating evaporation, and sodium hydroxide aqueous solution is slowly added until the pH value is more than orequal to 12; extracting the water phase with methyl tert-ether twice, combining the organic phase, washing with saturated brine once, drying with anhydrous sodium sulfate, concentrating, and distilling under reduced pressure to obtain the product 1-poxlene-8-thiol. The method solves the problems that in the prior art, the synthesis route of the 1-poxlene-8-thiol is complex, the lithium aluminum tetrahydrate in the raw material is expensive, the danger is high, and the prior method is not suitable for industrial production.

Synthesis process method of p-menon-1-ene-8-thiol

The invention discloses a synthesis process method of p-menon-1-ene-8-thiol, in particular to a novel synthesis process method for obtaining p-menon-1-ene-8-thiol by using cheap synthetic perfume alpha-terpineol obtained from turpentine oil as a raw material to be reacted with thioacetic acid and then adopting LiAlH4 for reduction. The synthesis process method has the advantages that the synthesisroute is short, the process operation is simple, raw materials and reagents are easy to obtain and cheap, the first reaction cycle is shortened, the yield is high, and more importantly, the cost is greatly reduced.

Simple synthetic protocols for tertiary alkyl and allyl thiols

Convenient preparative methods for tertiary alkyl and allyl thiols are described. Accordingly, thiolesters and thiocyanates, obtained from the reaction of SN1-active halides and appropriate zinc salts, on hydrolysis and LAH reduction respectively, afford the corresponding thiols in near quantitative yields. Besides the well known p-menth-1-ene-8-thiol, p-menthane-1-thiol, p-mentha-1,8-diene-6-thiol and 2-(2-phenyl)propane thiol have been prepared.