833446-03-0Relevant articles and documents
Synthesis of novel 2-aryl AICAR derivatives
Kohyama, Naoki,Katashima, Tomoyuki,Yamamoto, Yukio
, p. 2799 - 2804 (2007/10/03)
Novel 2-aryl AICAR (5-Amino-1-β-D-ribofuranosylimidazole-4- carboxamide) derivatives 8 were synthesized via the Suzuki-Miyaura cross-coupling reactions of 8-bromoadenosine. Following conversion of the adenine moiety of 4 to hypoxanthine (5) and the introduction of a MEM group, hydrolysis of 7 gave desired 2-aryl AICAR derivatives 8.