83408-66-6 Usage
Purpose
Medication used in the treatment of non-small cell lung cancer
Mechanism of action
Blocks the activity of a protein responsible for the growth and spread of cancer cells
Classification
Tyrosine kinase inhibitor
Administration
Taken orally in the form of a tablet
Target patient group
Patients who have not responded to other chemotherapy treatments
Side effects
Diarrhea, skin rash, and inflammation of the liver
Pregnancy recommendation
Not recommended for use in pregnant women due to potential harm to the developing fetus
Check Digit Verification of cas no
The CAS Registry Mumber 83408-66-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,4,0 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 83408-66:
(7*8)+(6*3)+(5*4)+(4*0)+(3*8)+(2*6)+(1*6)=136
136 % 10 = 6
So 83408-66-6 is a valid CAS Registry Number.
InChI:InChI=1/C34H24ClN5OS/c35-25-14-10-23(11-15-25)22-36-26-16-12-24(13-17-26)32-39-31-9-5-4-8-30(31)33(41)40(32)29-20-18-28(19-21-29)38-34(42)37-27-6-2-1-3-7-27/h1-22H,(H2,37,38,42)/b36-22+
83408-66-6Relevant articles and documents
Synthesis of 2--3-quinazolin-4-ones as CNS Agents
Shukla, J. S.,Rastogi, Renu
, p. 375 - 377 (2007/10/02)
A series of 2--3-arylquinazolin-4-ones (6-29) and 2--3-quinazolin-4-ones (30-35) have been prepared.The pharmacological screening results s