83487-19-8

Basic information

• Product Name: 1-Pyrrolidinecarboxylicacid,3-hydroxy-,methylester(9CI)
• Synonyms: 1-Pyrrolidinecarboxylicacid,3-hydroxy-,methylester(9CI);3-hydroxy-1-Pyrrolidinecarboxylic acid Methyl ester
• CAS NO: 83487-19-8
• Molecular Formula: C6H11NO3
• Molecular Weight: 0
• Product Categories: CARBOXYLICESTER
• Mol File: 83487-19-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Pyrrolidinecarboxylicacid,3-hydroxy-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylicacid,3-hydroxy-,methylester(9CI)(83487-19-8)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylicacid,3-hydroxy-,methylester(9CI)(83487-19-8)

Safety Data

• Hazardous Substances Data: 83487-19-8(Hazardous Substances Data)

Usage

Structure

A pyrrolidine ring with a carboxylic acid group at position 1 and a hydroxyl group at position 3, and a methyl ester group attached to the oxygen of the carboxylic acid.

Physical state

Colorless liquid

Molecular weight

145.16 g/mol

Use in pharmaceutical and chemical applications

It is used in the synthesis of drugs and other bioactive compounds and has the potential to be a valuable building block in the development of new pharmaceuticals.

Upstream product

• 56475-88-8 methyl 2-methoxypyrrolidine-1-carboxylate 
• 56475-80-0 N-(methoxycarbonyl)pyrrolidine 
• 79-22-1 methyl chloroformate 
• 111810-68-5 3-hydroxypyrrolidine hydrochloride 
• 76460-88-3 N-methoxycarbonyl-2,3-dihydropyrrole 

Relevant articles and documents

Room temperature hydroalkylation of electron-deficient olefins: sp 3 C-H functionalization via a Lewis acid-catalyzed intramolecular redox event

A practical method for the intramolecular hydroalkylation of electron-deficient olefins has been developed. The direct transformation of benzylic, tertiary, and sterically hindered secondary sp3 C-H bonds into C-C bonds under the action of a catalytic amount of a variety of Lewis acids is described. The mechanism of these transformations is proposed to involve a tandem hydride transfer/cyclization sequence. Copyright

Electroorganic Chemistry. 60. Electroorganic Synthesis of Enamides and Enecarbamates and Their Utilization in Organic Synthesis.

A variety of enecarbamates and enamides were synthesized from α-methoxy carbamates and α-methoxy amides prepared by anodic methoxylation of amine derivatives.Some new carbon-carbon bond-forming reactions and hydroxylation at the β position of amines have been accomplished by using these enecarbamates and enamides as key intermediates.Also, new synthetic routes of nicotinaldehyde and pyrrole derivatives have been exploited by utilizing anodic dimethoxylation of carbamates of piperidine and pyrrolidine, respectively.