834894-21-2 Usage
General Description
PF-562771 is a potent and selective small molecule inhibitor of FAK (focal adhesion kinase), a non-receptor tyrosine kinase that plays a key role in cell adhesion, migration, and proliferation. It has been shown to effectively inhibit the activity of FAK in cancer cells, leading to decreased cell proliferation and increased cell death. PF-562771 has also been found to suppress the phosphorylation of focal adhesion complexes and disrupt the formation of stress fibers, ultimately inhibiting the migration and invasion of cancer cells. Additionally, PF-562771 has demonstrated potential as a therapeutic agent for various cancers, including breast, lung, and pancreatic cancer, by targeting FAK-dependent signaling pathways involved in tumor progression and metastasis. Overall, PF-562771 shows promise as a potential treatment for cancer by inhibiting FAK activity and disrupting cancer cell migration and invasion.
Check Digit Verification of cas no
The CAS Registry Mumber 834894-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,4,8,9 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 834894-21:
(8*8)+(7*3)+(6*4)+(5*8)+(4*9)+(3*4)+(2*2)+(1*1)=202
202 % 10 = 2
So 834894-21-2 is a valid CAS Registry Number.
