83627-55-8

Basic information

• Product Name: N-Propyl-2-methylbenzenamine
• Synonyms: N-Propyl-2-methylaniline;N-Propyl-2-methylbenzenamine;N-Propyl-o-toluidine;Benzenamine, 2-methyl-N-propyl-
• CAS NO: 83627-55-8
• Molecular Formula: C₁₀H₁₅N
• Molecular Weight: 0
• Mol File: 83627-55-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Propyl-2-methylbenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Propyl-2-methylbenzenamine(83627-55-8)
• EPA Substance Registry System: N-Propyl-2-methylbenzenamine(83627-55-8)

Safety Data

• Hazardous Substances Data: 83627-55-8(Hazardous Substances Data)

Upstream product

• 107-08-4 1-iodo-propane 
• 95-53-4 o-toluidine 
• 15316-91-3 N-allyl-o-toluidine 
• 71-23-8 propan-1-ol 
• 102-69-2 tri-n-propylamine 
• 106-94-5 propyl bromide 
• 62-53-3 aniline 
• 74-85-1 ethene 
• 611-21-2 N,2-dimethylaniline 
• 3739-64-8 allyl n-butyl ether 
• 88-72-2 1-methyl-2-nitrobenzene 
• 107-12-0 propiononitrile 

Downstream Products

• 67103-28-0 C₂₁H₂₂N₂O₄ 
• 64062-59-5 3-(2-Methoxy-aethoxycarbonyl-amino)-phenyl-2-methyl-N-propylcarbanilat 
• 55240-20-5 C₁₁H₁₄ClNO 
• 13401-66-6 bis-(3-methyl-4-propylamino-phenyl)-methane 

Relevant articles and documents

Titanium-Catalyzed Hydroaminoalkylation of Ethylene

The first examples of titanium-catalyzed hydroaminoalkylation reactions of ethylene with secondary amines are presented. The reactions can be achieved with various titanium catalysts and they do not require the use of high pressure equipment. In addition, the first solid-state structure of a titanapyrrolidine that is formed by insertion of an alkene into the Ti?C bond of a titanaaziridine is reported.

Development of Quinoline-2,4(1H,3H)-diones as Potent and Selective Ligands of the Cannabinoid Type 2 Receptor

The cannabinoid type 2 receptors (CB2Rs) play crucial roles in inflammatory diseases. There has been considerable interest in developing potent and selective ligands for CB2R. In this study, quinoline-2,4(1H,3H)-dione analogs have been designed, synthesized, and evaluated for their potencies and binding properties toward the cannabinoid type 1 receptor (CB1R) and CB2R. C5- or C8-substituted quinoline-2,4(1H,3H)-diones demonstrate CB2R agonist activity, while the C6- or C7-substituted analogs are antagonists of CB2R. In addition, oral administration of 21 dose-dependently alleviates the clinical symptoms of experimental autoimmune encephalomyelitis in a mouse model of multiple sclerosis and protects the central nervous system from immune damage. Furthermore, the interaction modes predicted by docking simulations and the 3D-QSAR model generated with CoMFA may offer guidance for further design and modification of CB2R modulators.

Assembly of substituted 2-alkylquinolines by a sequential palladium-catalyzed Ci-N and Ci-C bond formation

Diversity: A range of substituted 2-alkylquinolines can be prepared in a general and efficient synthetic approach that employs mild reaction conditions (see scheme). The synthesis is based on a sequential palladium-catalyzed Ci-N and Ci-C bond formation, followed by palladium-catalyzed aromatization, and results in the formation of the desired compounds in one step. Copyright