83725-05-7

Basic information

• Product Name: 3-Acetamido-5-methylpyrazole
• Synonyms: 3-Acetamido-5-methylpyrazole;N-(5-methyl-1H-pyrazol-3-yl)acetamide;N-(5-Methyl-2H-pyrazol-3-yl)acetamide;N-(5-Methyl-1H-pyrazol-3-yl)
• CAS NO: 83725-05-7
• Molecular Formula: C6H9N3O
• Molecular Weight: 139.16
• Mol File: 83725-05-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 410.8°C at 760 mmHg
• Flash Point: 202.3°C
• Appearance: /
• Density: 1.261
• Vapor Pressure: 5.85E-07mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-Acetamido-5-methylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Acetamido-5-methylpyrazole(83725-05-7)
• EPA Substance Registry System: 3-Acetamido-5-methylpyrazole(83725-05-7)

Safety Data

• Hazardous Substances Data: 83725-05-7(Hazardous Substances Data)

Usage

General Description

3-Acetamido-5-methylpyrazole is a chemical compound that falls within the category of pyrazoles, which comprise a class of organic compounds that contain a 5-membered aromatic ring. The chemical formula for 3-Acetamido-5-methylpyrazole is C7H10N4O and features an acetamido group and a methyl group attached to different positions on the pyrazole ring. The properties and applications of this compound largely depend on its specific structure and the characteristics of these functional groups. Its preparation and uses include various fields, most commonly in medicinal chemistry and pharmaceuticals. However, details on its specific applications are limited, and further studies may reveal more about its potential uses and implications.

InChI:InChI=1/C6H9N3O/c1-4-3-6(9-8-4)7-5(2)10/h3H,1-2H3,(H2,7,8,9,10)

Upstream product

• 31230-17-8 3-methyl-5-aminopyrazole 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 854698-22-9 N-(5-methyl-4-nitro-1H-pyrazol-3-yl)acetamide 

Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the α2δ subunit of the voltage-gated calcium channel and the sigma-1 (σ1) receptor, to processes of preparation of such compounds,

MULTI-KINASE INHIBITOR COMPOUND, AND CRYSTAL FORM AND USE THEREOF

The present invention relates to a compound as represented by formula (I) or a pharmaceutically acceptable salt and stereoisomer thereof, wherein R1, R2, X, Y, P, W, and Ar are as defined in the description. The compound of formula (I) of the present invention can be used in the preparation of a drug for treating cancers mediated by abnormality of multi-kinases. Also provided is a crystal form I of a compound 4-(5-(2-chlorophenyl)-3-methyl-2,10-dihydropyrazolo[4,3-b]pyrido[4,3-e][1,4]diazepin-8-yl)morpholine, wherein in an X-ray powder diffraction pattern of crystal form I, there are characteristic peaks at 7.4±0.20, 17.9±0.2°, 18.9±0.2°, 19.4±0.2°, 21.5±0.2°, and 23.7±0.2°.

A class of pyrazolopyrimidine diazepine derivatives with antitumor effect

The present invention relates to the field of medicine, wherein a pyrazolopyrimidine diazepine derivative represented by a formula I can significantly inhibit three targets such as Aurora A, Aurora Band vascular endothelial growth factor receptor 2 (VEGFR2/KDR), or two or one of the three targets, and the pharmacological experiment results show that the pyrazolopyrimidine diazepine derivative hassignificant antitumor activity, can be used to be developed into antitumor drugs for treatment or control of malignant tumors, especially drugs for treatment or control of gastric cancer, liver cancer, lung cancer, breast cancer, colon cancer and the like. The formula I is defined in the specification.