84002-78-8

Basic information

• Product Name: (Z)-7-Pentyl-8-phenylselanyl-cyclooct-2-enone
• CAS NO: 84002-78-8
• Molecular Weight: 349.375
• Mol File: 84002-78-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-7-Pentyl-8-phenylselanyl-cyclooct-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-7-Pentyl-8-phenylselanyl-cyclooct-2-enone(84002-78-8)
• EPA Substance Registry System: (Z)-7-Pentyl-8-phenylselanyl-cyclooct-2-enone(84002-78-8)

Safety Data

• Hazardous Substances Data: 84002-78-8(Hazardous Substances Data)

Upstream product

• 35242-04-7 cis,cis-2,7-cyclooctadienone 
• 34837-55-3 Phenylselenyl bromide 
• 693-25-4 n-pentylmagnesium bromide 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 84048-14-6 (1S,5R)-N-((R)-1-phenylethyl)-1-n-amyl-9-azabicyclo (3.3.1) nonan-3-one 
• 84002-74-4 (1R,5S)-N-((R)-1-phenylethyl)-1-n-amyl-9-azabicyclo (3.3.1) nonan-3-one 
• 84002-73-3 N-Benzyladalinein 

Relevant articles and documents

ASYMMETRIC SYNTHESES OF THE LADYBUG ALKALOID ADALINE AND 1-METHYL-9-AZABICYCLO (3.3.1)NONAN-3-ONE

The double Michael addition of benzylamine to 3-alkyl-2,7-cyclooctadienones, followed by hydrogenolysis, affords bridgehead substituted 9-azabicyclo(3.3.1)nonan-3-ones.Use of (+)-α-methylbenzylamine in the addition leads to mixtures of diastereometric adducts in unequal amounts.Although the degree of asymmetric induction is low (10-20 percent ee), the diastereomers can be easily separated, affording pure enantiomeric forms of the ladybug alkaloid adaline 1 and the Euphorbia alkaloid 3.