840523-45-7Relevant articles and documents
Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1
Zhang, Xiaoyan,Urbanski, Maud,Patel, Mona,Zeck, Roxanne E.,Cox, Geoffrey G.,Bian, Haiyan,Conway, Bruce R.,Beavers, Mary Pat,Rybczynski, Philip J.,Demarest, Keith T.
, p. 5202 - 5206 (2007/10/03)
A series of benzo-fused heteroaryl-O-glucosides was synthesized and evaluated in SGLT1 and 2 cell-based functional assays. Indole-O-glucoside 10a and benzimidazole-O-glucoside 18 exhibited potent in vitro SGLT2 inhibitory activity.