842-80-8

Basic information

• Product Name: 2,4-bis(4-fluorophenyl)thiophene
• Synonyms: 2,4-bis(4-fluorophenyl)thiophene
• CAS NO: 842-80-8
• Molecular Weight: 272.318
• Mol File: 842-80-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4-bis(4-fluorophenyl)thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-bis(4-fluorophenyl)thiophene(842-80-8)
• EPA Substance Registry System: 2,4-bis(4-fluorophenyl)thiophene(842-80-8)

Safety Data

• Hazardous Substances Data: 842-80-8(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 405-99-2 para-fluorostyrene 
• 79314-41-3 C₁₆H₁₄F₂ 
• 615-37-2 ortho-methylphenyl iodide 
• 214907-24-1 [2-(4-fluorophenyl)vinyl]boronic acid 
• 31599-59-4 2-(diacetoxyiodo)toluene 
• 766-98-3 1-ethynyl-4-fluorobenzene 

Relevant articles and documents

Cu-catalyzed [2 + 2 + 1] cascade annulation of vinyl iodonium salts with elemental sulfur/selenium for the modular synthesis of thiophenes and selenophenes

A [2 + 2 + 1] annulation protocol has been established for the modular synthesis of 2,4-disubstituted thiophenes/selenophenes, with excellent regioselectivity. The reactions have been catalyzed by copper salt with elemental sulfur and selenium serving as

Transition-Metal-Free Sulfuration/Annulation of Alkenes: Economical Access to Thiophenes Enabled by the Cleavage of Multiple C-H Bonds

A novel, atom economical, and transition-metal-free strategy for the synthesis of thiophenes from substituted buta-1-enes with potassium sulfide has been presented. The reaction achieves double C-S bond formations via cleavage of multiple C-H bonds and provides an efficient approach to access various functionalized thiophenes. Moreover, the strategy can also be used for the synthesis of thiophenes from 1,4-diaryl-1,3-dienes. Mechanistically, DMSO plays a role of oxidant and S3?- in situ generated from K2S is involved.