844467-91-0Relevant articles and documents
Preparation method of phytol and intermediates thereof
-
Paragraph 0064-0099, (2021/03/18)
The invention discloses a preparation method of phytol and intermediates thereof, which comprises the following steps: (1) carrying out esterification rearrangement reaction on isophytol and anhydrideunder the action of perchlorate to obtain phytol ester; and (2) carrying out transesterification on the phytol ester to obtain the phytol. According to the preparation method disclosed by the invention, the total molar yield of the phytol can be up to 88.1%, the generation of potassium acetate or sodium acetate waste solids caused by a potassium hydroxide or sodium hydroxide hydrolysis process isavoided by adopting an ester exchange process, three wastes are effectively controlled, and the method is green and environment-friendly.
Full racemic phytol composition, and preparation method and application thereof
-
, (2020/12/10)
The present invention provides a full racemic phytol composition with high E-configuration content, a preparation method of the full racemic phytol composition and applications of the full racemic phytol composition in preparation of vitamin K1. The full racemic phytol composition comprises Z-configuration full racemic phytol and E-configuration full racemic phytol, wherein a ratio of Z/(Z+E) is less than or equal to 15%. The preparation method comprises the following steps: with isophytol as a raw material, performing halogenation, esterification, ester group removal reaction and the like toobtain the full racemic phytol composition with high E-configuration content.
Enantioselective Synthesis and Activity of All Diastereoisomers of (E)-Phytal, a Pheromone Component of the Moroccan Locust, Dociostaurus maroccanus
Guerrero, Angel,Ramos, Victoria Elena,López, Sergio,Alvarez, José María,Domínguez, Aroa,Coca-Abia, María Milagro,Bosch, María Pilar,Quero, Carmen
, p. 72 - 80 (2019/01/15)
The Moroccan locust, Dociostaurus maroccanus (Thunberg, 1815) (Orthoptera: Acrididae), is a polyphagous pest capable of inflicting large losses in agriculture under favorable environmental and climatic conditions. Currently, control of the pest relies solely on the application of conventional insecticides that have negative effects on the environment and human safety. In the search for a more rational, environmentally acceptable approach for locust control, we have previously reported that (Z/E)-phytal (1) is a male-produced candidate sex pheromone of this acridid. This molecule, with two stereogenic centers at C-7 and C-11, has four different diastereomers along with the Z/E stereochemistry of the double bond at C-2. In this paper, we present for the first time the enantioselective synthesis of the four diastereomers of (E)-phytal and their electrophysiological and behavioral activity on males and females. Our results demonstrate that the (R,R)-phytal is the most active diastereomer in both assays, significantly attracting females in a double-choice Y olfactometer, and confirming the previous chromatographic assignment as component of the sex pheromone of the Moroccan locust.