844470-80-0

Basic information

• Product Name: (aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride
• Synonyms: (aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride;(1S)CYCLOPROPYLPHENYLMETHYLAMINE-HCl;(S)-Cyclopropyl(phenyl)MethanaMine hydrochloride;(S)-C-Cyclopropyl-C-phenyl-methylamine hydrochloride;(S)-cyclopropyl(phenyl)methanamine;-Cyclopropyl(phenyl)
• CAS NO: 844470-80-0
• Molecular Formula: C10H13N.ClH
• Molecular Weight: 183.681
• Mol File: 844470-80-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride(844470-80-0)
• EPA Substance Registry System: (aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride(844470-80-0)

Safety Data

• Hazardous Substances Data: 844470-80-0(Hazardous Substances Data)

Usage

General Description

"(aS)-alpha-Cyclopropylbenzenemethanamine hydrochloride is a complex chemical compound. As its name suggests, it is a derived form of alpha-Cyclopropylbenzenemethanamine, a class of organic compounds known as benzenes, with a hydrochloride group. The hydrochloride addition typically makes the compound more water-soluble, and it is common for medicinal and bioactive compounds. (aS) signifies the stereochemistry of the compound, indicating that it is the 'aS' enantiomer. Precise details of its uses and properties may vary based on specifics of its formulation and application, but it's likely used in research or potentially in certain types of chemical synthesis or pharmaceutical development.

Upstream product

• 844470-77-5 (S)-2-[((S)-1-cyclopropyl-1-phenyl-methyl)-amino]-3-methyl-butan-1-ol 
• 3481-02-5 cyclopropyl phenyl ketone 
• 7555-72-8 cyclopropyl(phenyl)methanone oxime 

Downstream Products

• 1061198-20-6 N-((S)-cyclopropyl-phenyl-methyl)-3-methylsulfinyl-2-phenyl-quinoline-4-carboxamide 
• 1430473-02-1 (S)-N-(cyclopropyl(phenyl)methyl)-3-iodo-1H-indazole-5-carboxamide 

Relevant articles and documents

5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF

Provided herein is a compound of Formula (I), or pharmaceutically acceptable salt thereof, wherein R1, Y, X, and n are defined herein. Also provided herein are compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt thereof, e.g., in the treatment of heart disease.

PYRIMIDINEDIONE COMPOUNDS AGAINST CARDIAC CONDITIONS

Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.

COMPOUNDS HAVING ACTIVITY AT NK3 RECEPTOR AND USES THEREOF IN MEDICINE

The present invention relates to compounds of formula (I), a pharmaceutically acceptable salt, solvate or prodrug thereof: wherein R1 is phenyl optionally substituted by 1, 2 or 3 halogen atoms which halogen atoms may be the same or different; R2 is C1-6alkyl, C3-6cycloalkyl or acetyl; X is oxygen or sulphur; a is 1, 2 or 3; b is 0 or 1; c is 0, 1 or 2; R3 is hydrogen or C1-6alkyl; R4 is hydrogen, C1-6alkyl, haloC1-6alkyl, C1-4alkoxyC1-6alkyl, C3-6cycloalkyl or C3-6cycloalkylC1-6alkyl; R5 is hydrogen; or R5 and R3, together with the nterconnecting atoms, form a 4, 5 or 6 membered ring; R6 is phenyl or thienyl, either of which is optionally substituted by 1, 2 or 3 halogen atoms, which atoms may be the same or different; and z is 0, 1 or 2; wherein when z is 1 or 2, Z is a halogen atom, and wherein when z is 2 the halogen atoms may be the same or different. Also disclosed are processes for their preparation, pharmaceutical compositions containing them and heir use as medicaments particularly in treating disorders of the Central Nervous System (CNS).