84449-81-0

Basic information

• Product Name: 4-(2-PIPERIDIN-1-YLETHOXY)BENZOYL CHLORIDE HYDROCHLORIDE
• Synonyms: 4-(2-PIPERIDIN-1-YLETHOXY)BENZOYL CHLORIDE HYDROCHLORIDE;Benzoyl chloride,4-[2-(1-piperidinyl)ethoxy]-, hydrochloride (1:1)
• CAS NO: 84449-81-0
• Molecular Formula: C₃H₃NO₂
• Molecular Weight: 0
• Mol File: 84449-81-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-PIPERIDIN-1-YLETHOXY)BENZOYL CHLORIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-PIPERIDIN-1-YLETHOXY)BENZOYL CHLORIDE HYDROCHLORIDE(84449-81-0)
• EPA Substance Registry System: 4-(2-PIPERIDIN-1-YLETHOXY)BENZOYL CHLORIDE HYDROCHLORIDE(84449-81-0)

Safety Data

• Hazardous Substances Data: 84449-81-0(Hazardous Substances Data)

Usage

Uses

4-(2-Piperidinoethoxy)benzoyl Chloride Hydrochloride is a reactant used in the preparation of highly potent revertants of P-glycoprotein-associated MDR.

Upstream product

• 1738-36-9 2-methoxyacetonitrile 
• 79-10-7 acrylic acid 
• 280-57-9 1,4-diaza-bicyclo[2.2.2]octane 
• 7677-24-9 trimethylsilyl cyanide 
• 79-22-1 methyl chloroformate 
• 932399-72-9 7-fluoro-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 538342-27-7 7-methyl-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 932399-74-1 8-nitro-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 538342-20-0 8-chloro-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 538342-19-7 6-chloro-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 932399-77-4 5-chloro-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 1000847-63-1 8-trifluoromethyl-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 1000847-62-0 6-trifluoromethyl-3-methoxycarbonyl-4H-1,2-benzoxazine 
• 1000847-61-9 5-trifluoromethyl-3-methoxycarbonyl-4H-1,2-benzoxazine 

Relevant articles and documents

Hepta(methoxycarbonyl)cycloheptatriene halo derivatives

A reaction of potassium hepta(methoxycarbonyl)cycloheptatrienide with chlorine and bromine gave high yields of the corresponding chloroand bromohepta(methoxycarbonyl)cycloheptatrienes; the fluoro derivative was obtained by the exchange reaction of the corresponding bromide with silver fluoride. In contrast to the mentioned halides, the iodo derivative has proved unstable. Thermolysis of bromohepta(methoxycarbonyl)cycloheptatriene was studied, as well as its conversion to the azido and methoxy derivatives upon treatment with NaN3 or methanol.

Reaction of stabilised phosphorus ylides with nitrogen dioxide

The reaction of the stabilised ylides 14-23 with an excess of NO2 in CH2Cl2 at room temperature gives different results depending on the structure of the starting ylide. The monacyl ylides 14-16 give the corresponding α-oxo nitriles 4 together with Ph3PO · HNO3 (24) which has been fully characterised for the first time. Under the same conditions, the ylide 18 gives 2,4-dinitrobenzonitrile (26), Ph3PO, and benzoic acid. The other ylides examined all give 24 together with a variety of other products.

1,2λ3,3λ3-AZADIPHOSPHOLE EIN AROMATISCHES RINGSYSTEM MIT CIS-P=P-DOPPELBINDUNG 1λ3ρ3,λ3ρ3-DIPHOSPHOLE

By reaction of 1,2,4,5-tetrazinedicarboxylates with 4 mole tert-butylphosphaethyne the title compounds are formed in an unusual reaction sequence.