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84538-49-8

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84538-49-8 Usage

General Description

2-(piperidine-1-carbonyl)benzaldehyde is a chemical compound with the molecular formula C16H17NO2. It is an aldehyde derivative that contains a piperidine ring and a benzene ring, as well as a carbonyl group attached to the piperidine ring. This chemical is commonly used as a building block in organic synthesis and medicinal chemistry. It can be used as a key intermediate in the synthesis of various pharmaceuticals, such as antihistamines and antidepressants. Additionally, it has been studied for its potential as an anti-inflammatory and anti-cancer agent. Overall, 2-(piperidine-1-carbonyl)benzaldehyde has important applications in the fields of drug discovery and medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 84538-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,3 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 84538-49:
(7*8)+(6*4)+(5*5)+(4*3)+(3*8)+(2*4)+(1*9)=158
158 % 10 = 8
So 84538-49-8 is a valid CAS Registry Number.

84538-49-8Downstream Products

84538-49-8Relevant articles and documents

Photoreactive Composition, Reaction Product, and Method of Producing Reaction Product

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Paragraph 0342-0350, (2021/08/20)

A photoreactive composition including a base-reactive compound, a photobase generator that is represented by the following Formula (1) and that generates a base when irradiated with light, and at least one compound selected from the group consisting of a

Gold-catalyzed amide synthesis from aldehydes and amines in aqueous medium

Li, Gai-Li,Kung, Karen Ka-Yan,Wong, Man-Kin

supporting information; experimental part, p. 4112 - 4114 (2012/06/16)

An efficient gold-catalyzed amide synthesis from aldehydes and amines in aqueous medium under mild reaction conditions has been developed.

Effect of Nucleophilicity and Leaving Group Ability on the SN2 Reactions of Amines with (Acyloxy)alkyl α-Halides: A Product Distribution Study

Sloan, Kenneth B.,Koch, Suzanne A. M.

, p. 635 - 640 (2007/10/02)

The course of the reaction of amines with (acyloxy)alkyl α-halides has been found to depend on the nucleophilicity of the amines and the leaving group ability of the halides.More nucleophilic amines tended to give acylated products 2 from the reaction while less nucleophilic amines gave alkylated products 3.The use of a better leaving group also tended to favor the formation of a greater amount of alkylated product.These results have been compared to the observations of Westaway on the effect of leaving group ability and nucleophilicity on the bond lengths in the transit ion state of SN2 reactions.In addition, secondary amines have been shown to cause the rearrangement of 2-formylbenzamides to 3-amino-1(3H)-isobenzofuranones.

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