847259-60-3

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-methoxyphenyl)-6-methyl-2-oxo-, hydrazide
• CAS NO: 847259-60-3
• Molecular Formula: C13H16N4O3
• Molecular Weight: 276.295
• Mol File: 847259-60-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-methoxyphenyl)-6-methyl-2-oxo-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-methoxyphenyl)-6-methyl-2-oxo-, hydrazide(847259-60-3)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-methoxyphenyl)-6-methyl-2-oxo-, hydrazide(847259-60-3)

Safety Data

• Hazardous Substances Data: 847259-60-3(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 161374-07-8 ethyl 4-(4-methoxyphenyl)-6-methyl-1,2,3,4-tetrahydropyrimidin-2-one-5-carboxylate 

Downstream Products

• 1311274-12-0 N'-(5-cyano-1-methyl-6-oxo-4-phenylpyrimidin-2-yl)-4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carbohydrazide 
• 1311274-15-3 C₂₅H₂₂N₈O₆ 
• 1311274-14-2 C₂₆H₂₅N₇O₅ 
• 1311274-13-1 C₂₅H₂₂ClN₇O₄ 

Relevant articles and documents

Microwave assisted synthesis and pharmacological screening of novel 6-Methyl-2-oxo-4-substituted 5-(5-Phenyl-1,3,4-oxadiazole-2-yl)-1,2,3, 4-tetrahydropyrimidines

A simple and efficient method has been developed for the synthesis of various 1,3,4-oxadiazole derivatives prepared from DHPM using microwave irradiation technique. The series of 1,3,4-oxadiazole-2-yl-1,2,3,4- tetrahydropyrimidine-2(1H)-one derivatives synthesized, were structurally confirmed by analytical and spectral data and evaluated for there lipoxygenase inhibitory and antibacterial activities. The results showed that this skeletal framework exhibited marked potency as lipoxigenase inhibition and antibacterial agents. The most active lipoxigenase inhibitor and antibacterial agent was 6-methyl-2-oxo-4-(p-nitrophenyl)-5-(5-phenyl-1,3,4-oxadiazole-2-yl)-1,2,3,4- tetrahydropyrimidine.