84796-89-4

Basic information

• Product Name: Hexanoic acid, 4-oxo-2-(phenylthio)-
• CAS NO: 84796-89-4
• Molecular Formula: C12H14O3S
• Molecular Weight: 238.307
• Mol File: 84796-89-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 4-oxo-2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 4-oxo-2-(phenylthio)-(84796-89-4)
• EPA Substance Registry System: Hexanoic acid, 4-oxo-2-(phenylthio)-(84796-89-4)

Safety Data

• Hazardous Substances Data: 84796-89-4(Hazardous Substances Data)

Upstream product

• 2783-12-2 2-nitrobutene 
• 103-04-8 (phenylthio)acetic acid 

Downstream Products

• 344438-49-9 methyl 2-(1-methyl-2-oxocyclohexyl)-4-oxohexanoate 
• 84796-83-8 methyl 4-oxo-2-(phenylthio)hexanoate 

Relevant articles and documents

Michael Reaction of Conjugated Nitro Olefins with Carboxylic Acid Dianions and with Ester Enolates: New Synthesis of γ-Keto Acids and γ-Keto Esters

Base-sensitive conjugated nitro olefins 2 reacted with lithium dianions of carboxylic acids 3 or with lithium enolates of esters 4 at a low temperature of ca. -100 deg C, and subsequent treatment of the Michael adducts with aqueous acid yielded γ-keto acids 5 or esters 5' in a one-pot operation, respectively.Results of both the reactions have been compared.Some applications of the resulting γ-keto esters in organic synthesis have also been demonstrated in lactone synthesis and cyclenone annulation.