848307-25-5

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 3-(hydroxymethyl)-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S)-
• CAS NO: 848307-25-5
• Molecular Formula: C16H23NO3
• Molecular Weight: 277.364
• Mol File: 848307-25-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 3-(hydroxymethyl)-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 3-(hydroxymethyl)-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S)-(848307-25-5)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 3-(hydroxymethyl)-4-phenyl-, 1,1-dimethylethyl ester, (3R,4S)-(848307-25-5)

Safety Data

• Hazardous Substances Data: 848307-25-5(Hazardous Substances Data)

Usage

Class of chemical

Esters

Derivative

Pyrrolidinecarboxylic acid

Stereochemistry

3R,4S configuration

Usage

Pharmaceutical research and drug development, synthesis of organic compounds, key building block for production of new molecules with enhanced biological activity.

Upstream product

• 848307-24-4 (3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 848307-24-4 (3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine 
• 848307-26-6 (3R,4S)-3-formyl-4-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

NOVEL SPIROTROPANE COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds according to formula (I): wherein the radical R2 represents a hydrogen atom or one of the following structures: R, and R7_9are as herein defined, and wherein ring A represents a 5 or 6 membered heteroring involvi

SPIRO COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of formula I insert formula I from claim 1 wherein X, Y, Z, W, R1 and R2 as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.