848784-87-2

Basic information

• Product Name: Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-)
• Synonyms: Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-);Betulinic acid 3beta-O-alpha-L-rhamnopyranosyl;Betulinic acid 3β-O-alpha-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-alpha-L-arabinopyranoside;Betulinic acid 3beta-O-alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->4)]-alpha-L-arabinopyranoside;Lup-20(29)-en-28-oicacid,3-[-D-glucopyranosyl(1→4)[-L-rhaMnopyranosyl)(1→2)--L-arabinopyranosyl]oxy],(3,4)-)
• CAS NO: 848784-87-2
• Molecular Formula: C47H76O16
• Molecular Weight: 897.09674
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 848784-87-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 247-250℃
• Appearance: /
• Density: 1.36±0.1 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-)(CAS DataBase Reference)
• NIST Chemistry Reference: Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-)(848784-87-2)
• EPA Substance Registry System: Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-)(848784-87-2)

Safety Data

• Hazardous Substances Data: 848784-87-2(Hazardous Substances Data)

Usage

Description

Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) is a naturally occurring triterpenoid saponin that can be isolated from the root of Pulsatilla koreana. It is characterized by its unique glycosylation pattern involving β-D-glucopyranosyl, α-L-rhamnopyranosyl, and α-L-arabinopyranosyl moieties. Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) exhibits significant cytotoxic activity against various human solid cancer cell lines, making it a promising candidate for cancer therapy and drug development.

Uses

Used in Pharmaceutical Industry:
Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) is used as a cytotoxic agent for its potential anticancer properties. Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) has demonstrated the ability to selectively target and eliminate cancer cells while sparing normal cells, making it a valuable asset in the development of novel cancer therapies.
Used in Drug Discovery and Development:
Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) serves as a key starting material for the synthesis of various saponin-based drug candidates. Its unique structural features and biological activities can be further optimized and modified to develop more effective and targeted cancer treatments.
Used in Cancer Research:
Lup-20(29)-en-28-oic acid, 3-[β-D-glucopyranosyl(1→4)[a-L-rhaMnopyranosyl) (1→2)-a -L-arabinopyranosyl]oxy], (3β,4a)-) is utilized in cancer research to better understand the molecular mechanisms underlying its cytotoxic effects. By studying its interactions with cancer cells and signaling pathways, researchers can gain valuable insights into the development of new therapeutic strategies and drug targets for cancer treatment.