849773-63-3

Basic information

• Product Name: ARP 101
• Synonyms: Butanamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-, (2R)-
• CAS NO: 849773-63-3
• Molecular Formula: C20H26N2O5S
• Molecular Weight: 406.49584
• Mol File: 849773-63-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Solubility: <40.65mg/ml in DMSO; <10.16mg/ml in ethanol
• CAS DataBase Reference: ARP 101(CAS DataBase Reference)
• NIST Chemistry Reference: ARP 101(849773-63-3)
• EPA Substance Registry System: ARP 101(849773-63-3)

Safety Data

• Hazardous Substances Data: 849773-63-3(Hazardous Substances Data)

Upstream product

• 18667-97-5 (S)-2-acetoxy-3-methylbutanoic acid 
• 849773-57-5 (R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid 
• 849773-55-3 (R)-tert-butyl 2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoate 
• 704888-95-9 N-isopropoxy-1,1'-biphenyl-4-sulfonamide 
• 380886-48-6 tert-butyl (S)-2-acetoxy-3-methylbutanoate 
• 101756-78-9 (S)-tert-butyl 2-bromo-3-methylbutanoate 
• 3519-30-0 L-α-hydroxyisovaleric acid t-butyl ester 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 849773-59-7 (R)-N-(tert-butyldimethylsilyloxy)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide 

Relevant articles and documents

Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides

Ab initio calculations (B3LYP/Lanl2DZ level of theory) were performed in this study to determine all the structural and catalytic zinc parameters required in order to study MMPs and their complexes with hydroxamate inhibitors by means of the AMBER force f