853302-27-9Relevant articles and documents
Synthesis of PPAR agonist via asymmetric hydrogenation of a cinnamic acid derivative and stereospecific displacement of (S)-2-chloropropionic acid
Houpis, Ioannis N.,Patterson, Lawrence E.,Alt, Charles A.,Rizzo, John R.,Zhang, Tony Y.,Haurez, Michael
, p. 1947 - 1950 (2007/10/03)
(Chemical Equation Presented) The synthesis of the peroxime proliferator activated receptor (PPAR) α,γ-agonist (1) was accomplished with high enantio- and diastereoselectivity by employing an asymmetric hydrogenation strategy, of an α-alkoxy cinnamic acid