855292-39-6 Usage
General Description
2-(isoquinolin-1-yl)acetic acid is a chemical compound with the molecular formula C11H9NO2. It is a derivative of isoquinoline and has an acetic acid group attached to the nitrogen atom. 2-(ISOQUINOLIN-1-YL)ACETIC ACID has shown potential as a ligand for metal complexes and has been studied for its potential use in the field of medicinal chemistry, particularly in the development of antitumor agents. Additionally, it has been investigated for its role in the synthesis of other organic compounds and as a building block in the creation of heterocyclic molecules. The compound's unique structure and properties make it an area of interest for further research and potential applications in various fields of science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 855292-39-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,5,2,9 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 855292-39:
(8*8)+(7*5)+(6*5)+(5*2)+(4*9)+(3*2)+(2*3)+(1*9)=196
196 % 10 = 6
So 855292-39-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO2/c13-11(14)7-10-9-4-2-1-3-8(9)5-6-12-10/h1-6H,7H2,(H,13,14)
855292-39-6Relevant articles and documents
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides
Baruah, Pranjal K.,Dinsmore, Jason,King, Amber M.,Salomé, Christophe,De Ryck, Marc,Kaminski, Rafal,Provins, Laurent,Kohn, Harold
supporting information; experimental part, p. 3551 - 3564 (2012/07/28)
N-Benzyl 2-acetamido-2-substituted acetamides, where the 2-substituent is a (hetero)aromatic moiety, are potent anticonvulsants. We report the synthesis and whole animal pharmacological evaluation of 16 analogues where the terminal 2-acetyl group was removed to give the corresponding primary amino acid derivatives (PAADs). Conversion to the PAAD structure led to a substantial drop in seizure protection in animal tests, demonstrating the importance of the N-acetyl moiety for anticonvulsant activity. However, several of the PAADs displayed notable pain-attenuating activities in a mouse model.
