85553-44-2 Usage
General Description
2-[3-(Bromomethyl)phenyl]thiophene is a chemical compound with the molecular formula C12H9BrS. It is a thiophene derivative with a bromomethyl group and a phenyl ring attached to the thiophene ring. 2-[3-(Bromomethyl)phenyl]thiophene is used in organic synthesis and pharmaceutical research as a building block for creating other complex molecules. It is also known for its potential biological activities and is of interest in medicinal chemistry for the development of new drugs. As a brominated aromatic compound, it should be handled and stored with appropriate care to prevent potential health hazards and environmental contamination.
Check Digit Verification of cas no
The CAS Registry Mumber 85553-44-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,5 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 85553-44:
(7*8)+(6*5)+(5*5)+(4*5)+(3*3)+(2*4)+(1*4)=152
152 % 10 = 2
So 85553-44-2 is a valid CAS Registry Number.
85553-44-2Relevant articles and documents
New Methods of Formation of Meta-Substituted Aromatic Compounds
Adams, Julian,Belley, Michel
, p. 3878 - 3881 (2007/10/02)
The addition of organolithium reagents to the oxa tricyclic ketone 1 occurs stereospecifically to produce the corresponding tertiary carbinols 2a-d.When the alcohols 2a-d are treated with TiCl4, ring fragmentation and dehydration occur to produce good yields of 5,6-dihydrobenzaldehydes 3a-d.Oxidation of aldehydes 3a-d then leads to the corresponding meta-substituted benzaldehydes 4a-d.Alternatively, use of the Lewis acid Me2BBr did not stop at the dihydrobenzaldehyde stage.Tautomerization of the diene aldehydes 3a-d produced meta-substituted benzyl alcohols 7a-d or benzyl bromides 8a-d under prolonged reaction times.The addition of silica gel to the reactions accelerated the formation of the benzyl bromides.
