85613-52-1

Basic information

• Product Name: 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)-1,1-dimethylethyl]amino]-3-[4-[4-(2-thienyl)- 1H-imidazol-2-yl]phenoxy]-
• CAS NO: 85613-52-1
• Molecular Formula: C28H33N3O4S
• Molecular Weight: 507.654
• Mol File: 85613-52-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)-1,1-dimethylethyl]amino]-3-[4-[4-(2-thienyl)- 1H-imidazol-2-yl]phenoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)-1,1-dimethylethyl]amino]-3-[4-[4-(2-thienyl)- 1H-imidazol-2-yl]phenoxy]-(85613-52-1)
• EPA Substance Registry System: 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)-1,1-dimethylethyl]amino]-3-[4-[4-(2-thienyl)- 1H-imidazol-2-yl]phenoxy]-(85613-52-1)

Safety Data

• Hazardous Substances Data: 85613-52-1(Hazardous Substances Data)

Upstream product

• 70552-22-6 2-(p-hydroxyphenyl)-4-(2-thienyl)imidazole 
• 126007-93-0 Methanesulfonic acid 2-hydroxy-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)-phenoxy]-propyl ester 
• 91944-36-4 2-[4-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-phenyl]-5-thiophen-2-yl-1H-imidazole 
• 91944-37-5 3-[4-(5-Thiophen-2-yl-1H-imidazol-2-yl)-phenoxy]-propane-1,2-diol 
• 75561-47-6 1,1-dimethyl-2-(4,5-methoxyphenyl)ethylamine 
• 91944-39-7 3-phenoxy>-1,2-epoxypropane 

Relevant articles and documents

β1-Selective adrenoceptor antagonists: Examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class

A series of 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazoles is described. The compounds were investigated in vitro for β-adrenoceptor antagonism, and several examples were found to be selective for the β1-adrenoceptor. The structure-activity relationship exhibited by this series of compounds is discussed. (S)-2-[p-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-hydroxypropoxy]phenyl] -4-(2-thienyl)imidazole [(S)-13] was over 100 times more selective than atenolol for the β1-adrenergic receptor and has been selected for in-depth studies.