85664-56-8

Basic information

• Product Name: (Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide
• Synonyms: (Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide
• CAS NO: 85664-56-8
• Molecular Weight: 183.294
• Mol File: 85664-56-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide(85664-56-8)
• EPA Substance Registry System: (Z)-N-(cyclohexylmethylene)-2-methylpropan-2-amine N-oxide(85664-56-8)

Safety Data

• Hazardous Substances Data: 85664-56-8(Hazardous Substances Data)

Upstream product

• 51338-99-9 N-tert-butyl hydroxylamine acetate 
• 2043-61-0 cyclohexanecarbaldehyde 
• 16649-50-6 N-tert-Butylhydroxylamine 

Downstream Products

• 1612163-43-5 2-(tert-butyl(hydroxy)amino)-2-cyclohexyl-N,N-diisopropylacetamide 
• 1346238-39-8 (E)-N-(3-(cyclohex-1-en-1-yl)-1-cyclohexylprop-2-yn-1-ylidene)-2-methylpropan-2-amine oxide 
• 1291087-47-2 (E)-N-(1-cyclohexyl-3-phenylprop-2-yn-1-ylidene)-2-methylpropan-2-amine N-oxide 
• 85664-68-2 1-(benzoyloxy)cyclohexanecarboxaldehyde 
• 85664-65-9 1-<(2,2-dimethylpropanoyl)oxy>cyclohexanecarboxaldehyde 
• 85664-67-1 1-<(2-methylpropanoyl)oxy>cyclohexanecarboxaldehyde 
• 85664-66-0 1-(propanoyloxy)cyclohexanecarboxaldehyde 
• 56037-77-5 1-(acetyloxy)cyclohexanecarboxaldehyde 
• 15753-47-6 1-(hydroxymethyl)cyclohexanol 
• 642481-99-0 N-tert-butyl-N-[1-cyclohexyl-2-(4-isopropyl-4,5-dihydrooxazol-2-yl)-2-methylpropyl]hydroxylamine 
• 100812-17-7 N-<(1-methoxycarbonyl)oxy)cyclohexyl)methylidene>-1,1-dimethylethanamine 
• 85664-62-6 N-<<1-<(2,2-dimethylpropanoyl)oxy>cyclohexyl>-methylidene>-1,1-dimethylethanamine 
• 100812-13-3 1-<((1,1-dimethylethyl)amino)methyl>cyclohexyl-2,2-dimethylpropanoate 

Relevant articles and documents

Carbamoyl anion addition to nitrones

The addition of carbamoyl anions derived from N,N-disubstituted formamides and LDA to N-tert-butyl nitrones is described. The reaction was demonstrated with a variety of formamides and nitrones and provided a direct route to α-(N-hydroxy)amino amides. The use of a tert-leucinol derived chiral auxiliary on the nitrone provided products in good diastereoselectivity. Derivatization of the products by tert-butyl deprotection or N-deoxygenation was demonstrated.

α-Oxygenation of Aldehydes and Cyclic Ketones by Acylation-Rearrangement of Nitrones

The reaction of N-tert-butylnitrones (1a-e) of aldehydes and N-methylnitrones (2 and 3) of cyclic ketones with acid chlorides in the presence of triethylamine afforded α-acyloxy imines by rearrangement of N-vinyl-O-acylhydroxylamine intermediates.Hydrolysis of the α-acyloxy imines gave α-acyloxy aldehydes and ketones.The acylation-rearrangement reaction offers a new method for α-oxygenation of carbonyl compounds.