85665-60-7

Basic information

• Product Name: 3-(1,1-dimethylethyl)-5-(hydroxymethyl)oxazolidin-2-one
• Synonyms: 3-(1,1-dimethylethyl)-5-(hydroxymethyl)oxazolidin-2-one;Einecs 288-150-5
• CAS NO: 85665-60-7
• Molecular Formula: C₈H₁₅NO₃
• Molecular Weight: 173.2096
• EINECS: 288-150-5
• Mol File: 85665-60-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 343.336 °C at 760 mmHg
• Flash Point: 161.444 °C
• Appearance: /
• Density: 1.139 g/cm³
• Vapor Pressure: 4.56E-06mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: 3-(1,1-dimethylethyl)-5-(hydroxymethyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1,1-dimethylethyl)-5-(hydroxymethyl)oxazolidin-2-one(85665-60-7)
• EPA Substance Registry System: 3-(1,1-dimethylethyl)-5-(hydroxymethyl)oxazolidin-2-one(85665-60-7)

Safety Data

• Hazardous Substances Data: 85665-60-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H15NO3/c1-8(2,3)9-4-6(5-10)12-7(9)11/h6,10H,4-5H2,1-3H3

Upstream product

• 13080-65-4 2-methyl-N-(oxiran-2-ylmethyl)propan-2-amine 
• 124-38-9 carbon dioxide 
• 22741-52-2 1-tert-butylamino-2,3-dihydroxypropane 
• 105-58-8 Diethyl carbonate 
• 584-08-7 potassium carbonate 
• 75-64-9 tert-butylamine 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 13156-02-0 1-chloro-3-tert-butylamino-2-propanol 

Downstream Products

• 1612878-81-5 5-(4-benzhydryl-piperazin-1-ylmethyl)-3-tert-butyl-oxazolidin-2-one 
• 26921-17-5 timolol maleate 
• 26839-75-8 timolol 

Relevant articles and documents

Synthesis of Five-membered Heterocycles by Reactions of N-Substituted-2-aminomethyloxiranes with Heterocumulenes

Various five membered heterocyclic compounds were synthesized by the reactions of N-substituted-2-aminomethyloxiranes with several different heterocumulenes in good yields.

Substrate-Controlled Product Divergence: Conversion of CO2 into Heterocyclic Products

Substituted epoxy alcohols and amines allow substrate-controlled conversion of CO2 into a wide range of heterocyclic structures through different mechanistic manifolds. This new approach results in an unusual scope of CO2-derived products by initial activation of CO2 through either the amine or alcohol unit, thus providing nucleophiles for intramolecular epoxy ring opening under mild reaction conditions. Control experiments support the crucial role of the amine/alcohol fragment in this process with the nucleophile-assisted ring-opening step following an SNi pathway, and a 5-exo-tet cyclization, thus leading to heterocyclic scaffolds.

Asymmetric hydrolysis of (R, S)-5-acetoxymethyl-3-tert-butyl- oxazolidin-2-one with enzymes and microorganisms

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