856707-58-9

Basic information

• Product Name: (+)-(S)-methyl 2-cyclohexyl-2-(picolinamido)acetate
• Synonyms: (+)-(S)-methyl 2-cyclohexyl-2-(picolinamido)acetate
• CAS NO: 856707-58-9
• Molecular Weight: 276.335
• Mol File: 856707-58-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (+)-(S)-methyl 2-cyclohexyl-2-(picolinamido)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(S)-methyl 2-cyclohexyl-2-(picolinamido)acetate(856707-58-9)
• EPA Substance Registry System: (+)-(S)-methyl 2-cyclohexyl-2-(picolinamido)acetate(856707-58-9)

Safety Data

• Hazardous Substances Data: 856707-58-9(Hazardous Substances Data)

Upstream product

• 14328-51-9 (2S)-amino(cyclohexyl)ethanoic acid 
• 98-98-6 2-Picolinic acid 
• 145618-11-7 (S)-amino(cyclohexyl)acetic acid methyl ester 
• 14328-63-3 methyl (2S)-amino(cyclohexyl)ethanoate hydrochloride 

Downstream Products

• 856707-59-0 C₁₄H₁₈N₂O₃ 

Relevant articles and documents

Polycyclic Azetidines and Pyrrolidines via Palladium-Catalyzed Intramolecular Amination of Unactivated C(sp3)-H Bonds

A novel strategy to construct complex polycyclic nitrogen-containing heterocycles from aliphatic amines via picolinamide-assisted palladium-catalyzed C-H bond activation reaction was reported. The reaction exhibits broad substrate scope for the synthesis of various azabicyclic scaffolds, including azetidines and tropane-class alkaloids. Application of this method to naturally occurring (-)-cis-myrtanylamine, an unprecedented type of carbon-carbon bond activation, in which the electron-pair involved initiates an intramolecular "SN2-like" displacement of a cyclopalladium-fragment from a tertiary center, is described.

INHIBITORS OF HEPATITIS C VIRUS NS3/NS4A SERINE PROTEASE

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as me