857854-82-1Relevant articles and documents
Nitrogen-containing fused tricyclic derivative and application thereof
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Paragraph 0272; 0277-0279, (2020/05/08)
The invention discloses a nitrogen-containing fused tricyclic derivative and application thereof, and particularly relates to a novel nitrogen-containing fused tricyclic derivative and a pharmaceutical composition containing the nitrogen-containing fused tricyclic derivative, and the nitrogen-containing fused tricyclic derivative can be used as a selective adenosine A2A receptor antagonist. The invention also relates to a method for preparing the compound and the pharmaceutical composition and application of the compound and the pharmaceutical composition in preparation of drugs for treating adenosine A2A receptor related diseases, especially Parkinson's disease.
NEW PYRROLIDINE DERIVATIVES AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS
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Page/Page column 83, (2014/05/07)
The invention relates to new pyrrolidine derivatives of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
GLUCOPYRANOSYLOXY-SUBSTITUTED AROMATES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THE USE THEREOF, AND METHODS FOR PRODUCING THE SAME
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Page/Page column 26-27, (2010/02/12)
The invention relates to glucopyranosyloxy-substituted aromates of general formula (I), wherein R1 to R6 and R7a, R7b, R7c are defined according to patent claim 1. The invention also relates to the tautomers, stereoisomers, mixtures and salts of said aromates, especially the physiologically compatible salts comprising inorganic or organic acids and having valuable pharmacological properties, especially an inhibiting effect on the sodium-dependent glucose cotransporter SGLT2. The invention further relates to the treatment of diseases, especially metabolic diseases such as diabetes, and to the production of said compounds.