858001-69-1

Basic information

• Product Name: (2-AMINO-ETHYL)-UREA HCL
• Synonyms: (2-AMINO-ETHYL)-UREA HCL;(2-AMINO-ETHYL)-UREA HYDROCHLORIDE;(2-Amino-ethyl)-ureaxHCl
• CAS NO: 858001-69-1
• Molecular Formula: C3H10ClN3O
• Molecular Weight: 139.58
• Mol File: 858001-69-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 141-143°C
• Boiling Point: 255.7°C at 760 mmHg
• Flash Point: 108.4°C
• Appearance: /
• Vapor Pressure: 0.0127mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (2-AMINO-ETHYL)-UREA HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-ETHYL)-UREA HCL(858001-69-1)
• EPA Substance Registry System: (2-AMINO-ETHYL)-UREA HCL(858001-69-1)

Safety Data

• Hazardous Substances Data: 858001-69-1(Hazardous Substances Data)

Usage

General Description

(2-AMINO-ETHYL)-UREA HCL, also known as thiodiglycol, is a chemical compound with the molecular formula C4H12N4O2. It is a derivative of urea and is commonly used in the synthesis of biologically active molecules. (2-AMINO-ETHYL)-UREA HCL has been studied for its potential applications in the pharmaceutical and agricultural industries, particularly for its antimicrobial and antifungal properties. It is also used as a chelating agent in the metal and mining industry, as well as a chemical intermediate in the production of various polymers and resins. Additionally, (2-AMINO-ETHYL)-UREA HCL is utilized in the manufacturing of dyes, pigments, and adhesives. Overall, this compound has diverse industrial and commercial applications due to its unique chemical properties.

InChI:InChI=1/C3H9N3O.ClH/c4-1-2-6-3(5)7;/h1-2,4H2,(H3,5,6,7);1H

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Relevant articles and documents

Synthesis, structural characterization, and catalytic evaluation of phosphinoferrocene ligands bearing extended urea-amide substituents

New phosphinoferrocene ligands bearing extended polar amidourea pendants with the general formula Ph2PfcCONHCH2CH 2NHCONR2 (1; R2 = H2 (b), H/Et (c), Me2 (d), H/Ph (e)) and their model bis-amide Ph 2PfcCONHCH2CH2NHCOCH3 (1a) were prepared in good yields by amidation of 1′-(diphenylphosphino)ferrocene-1- carboxylic acid (Hdpf) with the appropriate amines in the presence of peptide coupling reagents. These ferrocene-based phosphinoureas were further employed as ligands in palladium(II) complexes with η3-allyl and NC-chelating supporting ligands: viz., [PdCl(η3-C 3H5)(1-κP)] (5a-e) and [PdCl(LNC)(1- κP)] (6a-e; LNC = [2-(dimethylamino-κN)methyl]phenyl- κC1). Both the free ligands and their Pd(II) complexes were characterized by spectroscopic methods (multinuclear NMR, IR, and MS) and by elemental analysis. The molecular structures of 1b·CH3OH, 1c, 5b,c, 6a, and two additional model complexes, [PdCl(η3-C 3H5)(Hdpf-κP)] (5f) and [PdCl(η3- C3H5)(Ph2PfcCONH2-κP)] (5g), were determined by single-crystal X-ray diffraction analysis. All Pd(II) complexes were evaluated as catalysts in the cross-coupling of boronic acids and acyl halides to give ketones in a toluene/water biphasic mixture. Extensive reaction studies with compound 5e, which not only exerts good catalytic activity but is also readily accessible in a defined crystalline form, demonstrated efficient coupling reactivity for unsaturated substrates such as (substituted) benzeneboronic acids and benzoyl chlorides. The results also revealed that reaction difficulties encountered with less reactive substrates (e.g., insoluble aromatic boronic acids and all saturated aliphatic boronic acids) can be avoided by properly selecting the reaction partners, for example through transposition of substituents between reaction partners. Three representative benzophenones (4-fluoro-, 4-nitro-, and 4,4′-dinitrobenzophenone) were structurally characterized by single-crystal X-ray crystallography.