858517-21-2

Basic information

• Product Name: (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride
• Synonyms: (4aR,10bR)- 3,4,4a,5,6,10b-hexahydro-2H-Naphth[1,2-b]-1,4-oxazin-9-ol, hydrochloride;(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-β][1,4]oxazin-9-ol Hydrochloride;(4aR,10bR)- 3,4,4a,5,6,10b-Hexahydro-2H-Naphth[1,2-β]-1,4-oxazin-9-ol, Hydrochloride;(4aS,10bS)-3,4,4a,5,6,10b-hexahydro-2H-Naphth[1,2-β]-1,4-oxazin-9-ol, Hydrochloride;(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol;(+)-HNO hydrochloride
• CAS NO: 858517-21-2
• Molecular Formula: C12H16ClNO2
• Molecular Weight: 205.25
• Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
• Mol File: 858517-21-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 310-315°C dec.
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• Stability: Hygroscopic, Temperature Sensitive
• CAS DataBase Reference: (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride(858517-21-2)
• EPA Substance Registry System: (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride(858517-21-2)

Safety Data

• Hazardous Substances Data: 858517-21-2(Hazardous Substances Data)

Usage

Description

(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride is a complex organic compound with a unique hexahydro-naphtho-oxazin structure. It is characterized by its hydrochloride salt form, which contributes to its chemical properties and potential applications.

Uses

Used in Pharmaceutical Industry:
(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride is used as a dopamine agonist for its potential therapeutic effects on various conditions related to dopamine deficiency.
Used in Medical Imaging:
(+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol, Hydrochloride is used as a precursor for the PET radiotracer, 11C-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol. This radiotracer is valuable for medical imaging, particularly in Positron Emission Tomography (PET) scans, to visualize and assess dopamine receptor activity in the brain. This can aid in the diagnosis and monitoring of neurological disorders associated with dopamine dysregulation, such as Parkinson's disease.