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86-58-8

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86-58-8 Usage

Uses

Different sources of media describe the Uses of 86-58-8 differently. You can refer to the following data:
1. suzuki reaction
2. Reactant involved in:C-H and C-S bond activationsSynthesis of pyridazine via sequential amination / Suzuki coupling / alkylation reactionsSuzuki-Miyaura coupling reactions for synthesis of biaryl monophosphorus ligands, fused tricyclic oxa-quinolones, or substituted β-amino acidsCopper-catalyzed azidation with sodium azideStudies of the affect of fluoride on the stability of boronic acids during click reactions

Check Digit Verification of cas no

The CAS Registry Mumber 86-58-8 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 86-58:
(4*8)+(3*6)+(2*5)+(1*8)=68
68 % 10 = 8
So 86-58-8 is a valid CAS Registry Number.

86-58-8 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Detail
  • Alfa Aesar

  • (L19640)  Quinoline-8-boronic acid, 99%   

  • 86-58-8

  • 250mg

  • 763.0CNY

  • Detail
  • Alfa Aesar

  • (L19640)  Quinoline-8-boronic acid, 99%   

  • 86-58-8

  • 1g

  • 2121.0CNY

  • Detail
  • Aldrich

  • (542865)  8-Quinolinylboronicacid  technical grade

  • 86-58-8

  • 542865-250MG

  • 656.37CNY

  • Detail
  • Aldrich

  • (542865)  8-Quinolinylboronicacid  technical grade

  • 86-58-8

  • 542865-1G

  • 1,623.96CNY

  • Detail

86-58-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Quinolinylboronic acid

1.2 Other means of identification

Product number -
Other names Quinoline-8-boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86-58-8 SDS

86-58-8Related news

Determination of trace alkaline phosphatase by affinity adsorption solid substrate room temperature phosphorimetry based on wheat germ agglutinin labeled with 8-Quinolineboronic acid (cas 86-58-8) phosphorescent molecular switch and prediction of diseases07/16/2019

The 8-quinolineboronic acid phosphorescent molecular switch (abbreviated as PMS-8-QBA. Thereinto, 8-QBA is 8-quinolineboronic acid, and PMS is phosphorescent molecular switch) was found for the first time. PMS-8-QBA, which was in the “off” state, could only emit weak room temperature phosphore...detailed

8-Quinolineboronic acid (cas 86-58-8) as a potential phosphorescent molecular switch for the determination of alpha-fetoprotein variant for the prediction of primary hepatocellular carcinoma07/15/2019

8-Quinolineboronic acid phosphorescent molecular switch (8-QBA-PMS) in the “off” state emitted weak room temperature phosphorescence (RTP) of 8-QBA on the acetylcellulose membrane (ACM) with the perturbation of Pb2+. When 8-QBA-PMS was used to label concanavalin agglutinin (Con A) to form 8-QB...detailed

86-58-8Relevant articles and documents

-

Letsinger,Dandegaonker

, p. 498,501 (1959)

-

Silicon-bridged metallocene complex containing nitrogen heterocyclic ring structures and application thereof

-

Paragraph 0045-0048, (2020/06/04)

The invention relates to a preparation method and application of an olefin polymerization reaction catalyst, in particular to a silicon-bridged metallocene complex with nitrogen heterocyclic ring structures and application thereof. Molecules of the designed novel silicon-bridged metallocene complex contain three different nitrogen heterocyclic ring structures, and the distances from nitrogen atomsto a metal center are different, so that different chemical environments are provided for the metal center, and the metallocene complex with a novel structure is constructed. By changing a skeleton structure and a substituent group, the three-dimensional effect and the electronic effect of the metallocene complex can be conveniently regulated and controlled, the catalytic performance is regulatedand controlled, and polyolefin high polymer materials with different structures and properties are prepared.

Pyridin-2(1H)one derivatives: A possible new class of therapeutics for mechanical allodynia

Abrunhosa-Thomas, Isabelle,Anizon, Fabrice,Artola, Alain,Dallel, Radhouane,Descheemaeker, Amélie,Giraud, Francis,Moreau, Pascale,Nauton, Lionel,Pinto-Pardo, Nicolas,Théry, Vincent,Visseq, Alexia

, (2019/12/24)

Mechanical Allodynia (MA), a frequent chronic pain symptom caused by innocuous stimuli, constitutes an unmet medical need, as treatments using analgesics available today are not always effective and can be associated with important side-effects. A series of 3,5-disubstituted pyridin-2(1H)-ones was designed, synthesized and evaluated in vivo toward a rat model of inflammatory MA. We found that the series rapidly and strongly prevented the development of MA. 3-(2-Bromophenyl)-5-(phenylamino)pyridin-2(1H)-one 69, the most active compound of the series, was also able to quickly reverse neuropathic MA in rats. Next, when 69 was evaluated toward a panel of 50 protein kinases (PK) in order to identify its potential biological target(s), we found that 69 is a p38α MAPK inhibitor, a PK known to contribute to pain hypersensitivity in animal models. 3,5-Disubstituted pyridin-2(1H)-ones thus could represent a novel class of analgesic for the treatment of MA.

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