860024-94-8 Usage
General Description
1H-Indole-1-carboxylic acid, 5-(2-chloroethyl)-2,3-dihydro-, 1,1-diMethylethyl ester, also known as topotecan, is a synthetic derivative of camptothecin, a natural product isolated from the Chinese tree Camptotheca acuminate. It is a chemotherapeutic agent used in the treatment of various cancers, including ovarian, cervical, and small cell lung cancer. Topotecan works by inhibiting topoisomerase I, an enzyme that is essential for DNA replication and repair, thereby preventing the growth of cancer cells. It is administered intravenously and has shown promising results in the treatment of advanced cancers, particularly when other treatments have failed. However, like many chemotherapeutic agents, topotecan can cause adverse effects, such as nausea, vomiting, diarrhea, and myelosuppression.
Check Digit Verification of cas no
The CAS Registry Mumber 860024-94-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,0,2 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 860024-94:
(8*8)+(7*6)+(6*0)+(5*0)+(4*2)+(3*4)+(2*9)+(1*4)=148
148 % 10 = 8
So 860024-94-8 is a valid CAS Registry Number.
