86197-47-9 Usage
Description
Dopexamine is a dopamine analog useful in the treatment of acute congestive heart
failure. Its biochemical actions include the stimulation of beta2 and peripheral dopamine
receptors, as well as the inhibition of neuronal uptake of norepinephrine. The resultant
effect is an increase in cardiac output mediated by afterload reduction, increased blood
flow and positive inotropism following iv infusion.
Uses
Cardiovascular agent.
Brand name
Dopacard
Check Digit Verification of cas no
The CAS Registry Mumber 86197-47-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,1,9 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 86197-47:
(7*8)+(6*6)+(5*1)+(4*9)+(3*7)+(2*4)+(1*7)=169
169 % 10 = 9
So 86197-47-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H32N2O2/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2
86197-47-9Relevant articles and documents
Formulations
-
, (2008/06/13)
There is described a mixture of 4-[2-(6-(2-phenylethylamino)hexylamino)ethyl]-1,2-benzenediol, or 4-[2-(6-(2-chlorophenyl)ethylamino)hexylamino)ethyl]-1,2-benzenediol or a pharmaceutically acceptable acid addition salt of either thereof or as active ingredient, and a physiologically acceptable acid. There is also described a method of preparing a solid form of the active ingredient, which comprises freeze drying an aqueous solution of the mixture, and a freeze dried composition containing the active ingredient prepared by the method. The mixtures are useful as pharmaceuticals, e.g. in the treatment of cardiovascular conditions.