863600-81-1

Basic information

• Product Name: cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole
• Synonyms: cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole;endo-5-Amino-cis-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester
• CAS NO: 863600-81-1
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 224.2994
• Mol File: 863600-81-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole(863600-81-1)
• EPA Substance Registry System: cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole(863600-81-1)

Safety Data

• Hazardous Substances Data: 863600-81-1(Hazardous Substances Data)

Usage

General Description

Cis-5-amino-2-Boc-hexahydro-cyclopenta[c]pyrrole is a chemical compound with a unique structure. It is a derivative of the cyclic compound hexahydro-cyclopenta[c]pyrrole, and its structure includes an amino group and a Boc (tert-butoxycarbonyl) protecting group. The Boc group is often used to protect amine groups during organic synthesis. cis-5-AMino-2-Boc-hexahydro-cyclopenta[c]pyrrole has potential applications in pharmaceutical research and organic chemistry as a building block for the synthesis of more complex molecules. Its specific properties and reactivity make it a valuable tool for the development of new drugs and materials.

Upstream product

• 42268-68-8 allylpropargylamine 
• 147528-20-9 N-(tert-butoxycarbonyl)-N-allyl-3-amino-1-propyne 
• 863600-79-7 tert-butyl (cis-exo)-5-(benzylamino)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate 
• 146231-54-1 (3aR,6aS)-tert-butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 

Downstream Products

• 1280666-00-3 tert-butyl (cis-exo)-5-benzyloxycarbonylamino-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate 
• 1280666-02-5 benzyl (cis-exo)-N-[1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrol-5-yl]carbamate 
• 1280666-04-7 benzyl (cis-exo)-N-[2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]carbamate 

Relevant articles and documents

DIHYDROPTERIDINONE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

Dihydroperidinone derivatives, preparation process and pharmaceutical use thereof are disclosed. Specially, new dihydroperidinone derivatives represented by general formula (I), wherein each substituent of the general formula (I) is defined as in the description, their preparation process, pharmaceutical compositions comprising said derivatives and their use as therapeutical agents, especially as Plk kinase inhibitors are disclosed.

Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc

The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the 3-amino-8-azabicyclo[3.2.1]octane found in the CCR5 antagonist maraviroc.

Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity

The present application describes modulators of MCP-1 of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, wherein X, Z, a, b, c, d, n, R1, R2, R3, R4, R5, R10, R