864433-75-0

Basic information

• Product Name: 2-Ethyl-3-[(E)-(3-phenyl-acryloyl)]-chromen-4-one
• CAS NO: 864433-75-0
• Molecular Weight: 304.345
• Mol File: 864433-75-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Ethyl-3-[(E)-(3-phenyl-acryloyl)]-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethyl-3-[(E)-(3-phenyl-acryloyl)]-chromen-4-one(864433-75-0)
• EPA Substance Registry System: 2-Ethyl-3-[(E)-(3-phenyl-acryloyl)]-chromen-4-one(864433-75-0)

Safety Data

• Hazardous Substances Data: 864433-75-0(Hazardous Substances Data)

Upstream product

• 102-92-1 Cinnamoyl chloride 
• 118-93-4 o-hydroxyacetophenone 
• 74766-95-3 2-acetylphenyl (E)-3-phenylacrylate 
• 123-62-6 propionic acid anhydride 
• 205308-02-7 (E)-1-(2-hydroxyphenyl)-5-phenylpent-4-ene-1,3-dione 

Downstream Products

• 864433-82-9 2-Ethyl-3-[(E)-1-hydroxy-3-phenyl-prop-2-en-(Z)-ylidene]-chroman-4-one 

Relevant articles and documents

Synthesis of 3-alkenyl-2-arylchromones and 2,3-dialkenylchromones via acid-catalysed retro-Michael ring opening of 3-acylchroman-4-ones

3-Acylchromones and 3-acylflavones, readily available by acylation of 2′-hydroxydibenzoylmethane with acid anhydrides in the presence of base, undergo efficient conjugate reduction with NaBH4 in pyridine to give the corresponding chroman-4-ones/flavanones in high yields. The reduction is both regio- and chemoselective. Treatment of the chroman-4-ones with MeSO 3H generates the 3-alkenyl-2-arylchromones by a dehydrative rearrangement initiated by retro-Michael cleavage of the pyranone ring. This reduction-rearrangement sequence can be extended to 2-alkyl-3-alkenoylchromones to generate 3-alkenyl-2-styrylchromones, the first examples of 2,3-dialkenylchromones.