86447-11-2

Basic information

• Product Name: 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid
• Synonyms: 1-[(tert-butoxy)carbonyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid;1-[(2-methylpropan-2-yl)oxycarbonyl]-3,6-dihydro-2h-pyridine-5-carboxylic Acid;1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid
• CAS NO: 86447-11-2
• Molecular Formula: C₁₁H₁₇NO₄
• Molecular Weight: 227.26
• Mol File: 86447-11-2.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 356.942°C at 760 mmHg
• Flash Point: 169.673°C
• Appearance: /
• Density: 1.207g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid(86447-11-2)
• EPA Substance Registry System: 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid(86447-11-2)

Safety Data

• Hazardous Substances Data: 86447-11-2(Hazardous Substances Data)

Usage

General Description

1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid, also known as Boc-THP-3-carboxylic acid, is a chemical compound with a molecular formula C13H19NO4. It is a carboxylic acid derivative of tetrahydropyridine and is commonly used in organic synthesis as a building block for pharmaceuticals and other organic compounds. The "Boc" in its name stands for tert-butyloxycarbonyl, a protective group often used in organic chemistry to temporarily protect amines from unwanted reactions. 1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid is an important intermediate in the synthesis of various biologically active molecules and is widely used in the pharmaceutical and chemical industries. It is a white to off-white crystalline solid at room temperature and is soluble in organic solvents such as methanol and dichloromethane.

InChI:InChI=1/C11H17NO4/c1-11(2,3)16-10(15)12-6-4-5-8(7-12)9(13)14/h5H,4,6-7H2,1-3H3,(H,13,14)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 6027-91-4 1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride 
• 125097-83-8 methyl 1-tert-butoxycarbonyl-1,2,5,6-tetrahydropyridine-3-carboxylate 
• 498-96-4 guvacine 
• 495-19-2 norarecoline 
• 92600-27-6 1-(1-chloroethyl) 3-methyl 5,6-dihydropyridine-1,3(2H)-dicarboxylate 
• 300-08-3 arecoline hydrobromide 
• 7646-93-7 potassium hydrogensulfate 
• 126114-09-8 1-(tert-butyl) 3-ethyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate 
• 86447-10-1 methyl N-2,2,2-trichloroethyloxycarbonyl-1,2,5,6-tetrahydropyridine-3-carboxylate 
• 63-75-2 arecoline 
• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 
• 4644-61-5 ethyl 4-piperidone-3-carboxylate hydrochloride 
• 6027-92-5 guvacine hydrobromide 

Downstream Products

• 915233-33-9 5-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 88495-54-9 (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid 
• 163438-09-3 (R)-1-Boc-nipecotic acid 
• 885693-20-9 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 915233-34-0 5-[3-(4-fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-1,2,3,6-tetrahydro-pyridine hydrochloride 

Relevant articles and documents

IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS

The invention provides novel imidazopyrazine derivatives having the general formula (I), wherein A and R1 to R11 are as described herein NA (I) and pharmaceutically acceptable salts thereof.5 Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS

The invention provides novel imidazopyrazine derivatives having general formula (I), wherein R1 to R11 are as described herein, and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and related diseases.

NOVEL IMIDAZOPYRAZINE DERIVATIVES

The invention provides novel imidazopyrazine derivatives having the general formula (I), wherein A and R1 to R11 are as described herein (I) and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and related diseases.