864680-71-7

Basic information

• Product Name: 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl
• Synonyms: 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl;3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one;3-(4-AMinophenyl)-1,2,4-oxadiazol-5(4H)-one hydrochloride;3-(4-aminophenyl)-1,2,4-Oxadiazol-5(2H)-one;1,2,4-Oxadiazol-5(2H)-one,3-(4-aminophenyl)-
• CAS NO: 864680-71-7
• Molecular Formula: C₈H₇N₃O₂
• Molecular Weight: 213.62102
• Mol File: 864680-71-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 314.543 °C at 760 mmHg
• Flash Point: 144.031 °C
• Appearance: /
• Density: 1.55 g/cm³
• PKA: 7.44±0.20(Predicted)
• CAS DataBase Reference: 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl(864680-71-7)
• EPA Substance Registry System: 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl(864680-71-7)

Safety Data

• Hazardous Substances Data: 864680-71-7(Hazardous Substances Data)

Usage

General Description

3-(4-aminophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl is a chemical compound that is a derivative of oxadiazole. It is a white crystalline powder that is soluble in water and organic solvents. 3-(4-aMinophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl is a potential drug candidate with various pharmacological effects, including anti-inflammatory, analgesic, and antipyretic properties. It is also being researched for its potential use in the treatment of neurodegenerative diseases and as an anticonvulsant. Additionally, 3-(4-aminophenyl)-1,2,4-oxadiazol-5(4H)-one-HCl is being studied for its antimicrobial and antitumor activities. Due to its diverse pharmacological properties, this compound is of interest to researchers in the fields of medicine and pharmaceutical development.

Upstream product

• 105-58-8 Diethyl carbonate 
• 19932-97-9 3-p-nitrophenyl-4,5-dihydro-1,2,4-oxadiazol-5-one 
• 277319-62-7 4-amino-N'-hydroxybenzimidamide 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 1094107-30-8 C₂₂H₂₄N₄O₅ 
• 1418267-54-5 2-oxo-2-( 4-(5-oxo-4,5-dihydro-1 ,2,4-oxadiazol-3-yl)phenylamino )-1-( 4'(trifluoromethoxy)biphenyl-3-yl)ethyl acetate 

Relevant articles and documents

Substituted Oxopyridine Derivatives and Use Thereof in the Treatment of Cardiovascular Disorders

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Substituted oxopyridine derivatives and use thereof as factor XIA/plasma

The invention relates to substituted oxopyridine derivatives of formula (I), in which n stands for the number 1 or 2, A stands for -N(R2)- or -CH2-, R1 stands for a group of formula (II), R3 and R4 stand for hydrogen, and R5 stands for a group of formula (III) or (IV), methods for producing said substituted oxopyridine derivatives, and use of said substituted oxopyridine derivatives to produce drugs for treating and/or preventing diseases, in particular cardiovascular diseases, preferably thrombotic or thromboembolic diseases, and edemas and ophthalmologic diseases.

INDAZOLE DERIVATIVES

The invention is concerned with novel indazole derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in the claims, as well as physiologic