864943-22-6

Basic information

• Product Name: (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide
• Synonyms: (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide;(R)-3,3′-Bis(9-phenanthryl)-1,1′-binaphthalene-2,2′-diyl hydrogen phosphate;(R)-3,3'-Bis(9-phenanthrenyl)-1,1'-binaphthyl-2,2'-diyl Hydrogen Phosphate;(11bS)-4-hydroxy-2,6-di(phenanthren-9-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide;(11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-4-oxidedinaphtho[ 2,1-d:1',2'-f][1,3,2]dioxaphosphepin;(11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-4-oxide,99%e.e.
• CAS NO: 864943-22-6
• Molecular Formula: C48H29O4P
• Molecular Weight: 700.715221
• Mol File: 864943-22-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 390-400°C
• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• Storage Temp.: ?20°C
• PKA: 1.11±0.20(Predicted)
• CAS DataBase Reference: (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide(864943-22-6)
• EPA Substance Registry System: (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide(864943-22-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 864943-22-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide is used as a catalyst for enantioselective reactions, which are crucial for the synthesis of chiral pharmaceutical compounds. Its ability to selectively catalyze reactions can lead to the production of enantiomerically pure drugs, reducing side effects and improving therapeutic outcomes.
Used in Chemical Synthesis:
Asymmetric hydrogenation cascade
Enantioselective Friedel-Crafts reaction
Asymmetric hydrogenation of 2-substituted quinolines
Chiral Broensted acid catalyzed enantioselective α-aminoxylation of ene carbamates
Preparation of β-carbolines via diastereoand enantioselective N-acyliminium cyclization cascades of tryptamines and keto acids/esters
Asymmetric transfer hydrogenation of substituted quinoxalines
These applications highlight the versatility of (11bR)-2,6-Di-9-phenanthrenyl-4-hydroxy-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-oxide as a catalyst in different types of chemical reactions, enabling the synthesis of a wide range of enantioselective products.