865300-93-2

Basic information

• Product Name: [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amine
• Synonyms: [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amine
• CAS NO: 865300-93-2
• Molecular Weight: 283.461
• Mol File: 865300-93-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amine(865300-93-2)
• EPA Substance Registry System: [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amine(865300-93-2)

Safety Data

• Hazardous Substances Data: 865300-93-2(Hazardous Substances Data)

Upstream product

• 102191-92-4 tert-butyldimethylsiloxyacetaldehyde 
• 140-75-0 para-fluorobenzylamine 
• 459-57-4 4-fluorobenzaldehyde 
• 101711-55-1 2‐((tert‐butyldimethylsilyl)oxy)ethan‐1‐amine 
• 22116-33-2 2-(4-fluoro-benzyl-amino)-ethanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1616924-78-7 5-benzyloxy-6-hydroxy-2-(1-phenylcyclopentylmethyl)pyrimidine-4-carboxylic acid [2-(tert-butyldimethylsilanyloxy)ethyl](4-fluorobenzyl)amide 
• 922159-46-4 5,6-bis-(4-methoxy-benzyloxy)-2-p-tolyl-pyrimidine-4-carboxylic acid [2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-(4-fluoro-benzyl)-amide 
• 895134-22-2 4-benzyloxy-3-methoxy-pyridine-2-carboxylic acid [2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-(4-fluoro-benzyl)-amide 

Relevant articles and documents

Photocatalyzed cascade Meerwein addition/cyclization of: N -benzylacrylamides toward azaspirocycles

A visible-light-induced cascade Meerwein addition/cyclization of alkenes involving C-F bond cleavage was developed. This method offers a rapid access to azaspirocyclic cyclohexadienones from N-benzylacrylamides via C-F bond cleavage applying H2O as an external oxygen source, allowing for the incorporation of various aromatic moieties originating from aryldiazonium salts.

ANTIVIRAL COMPOUNDS

The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

HIV INTEGRASE INHIBITORS

Pyridopyrazine- and pyrimidopyrazine-dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dihydroxypyridine carboxamides are of Formula (I); wherein G, Q, bond a, R5, R6 and R