865546-36-7

Basic information

• Product Name: 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE
• Synonyms: 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE;1-(3-pyridinyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine(SALTDATA: FREE)
• CAS NO: 865546-36-7
• Molecular Formula: C12H13N3
• Molecular Weight: 199.25
• Mol File: 865546-36-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 366.4°C at 760 mmHg
• Flash Point: 175.4°C
• Appearance: /
• Density: 1.24g/cm³
• Vapor Pressure: 1.47E-05mmHg at 25°C
• Refractive Index: 1.674
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE(865546-36-7)
• EPA Substance Registry System: 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE(865546-36-7)

Safety Data

• Hazardous Substances Data: 865546-36-7(Hazardous Substances Data)

Usage

Description

1-Pyridin-3-yl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine is a chemical compound characterized by a tetrahydropyrrolopyrazine structure with a pyridine group attached at position 3. This unique structure endows it with potential pharmacological properties, making it a valuable building block in the pharmaceutical industry for the synthesis of biologically active molecules. Its chemical properties and potential biological activities position it as a promising tool for researchers in medicinal chemistry and drug design.

Uses

Used in Pharmaceutical Industry:
1-Pyridin-3-yl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine is used as a building block for the synthesis of various biologically active molecules due to its unique tetrahydropyrrolopyrazine structure with a pyridine group. 1-PYRIDIN-3-YL-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZINE serves as a key component in the development of new drugs, contributing to the discovery and creation of novel therapeutic agents with potential applications in treating various diseases and conditions.
In Drug Discovery and Development:
1-Pyridin-3-yl-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine is utilized for its potential pharmacological properties, which make it a valuable asset in drug discovery and development. Its unique structure allows for the exploration of new chemical entities and the enhancement of existing drug molecules, leading to improved efficacy, selectivity, and safety profiles in therapeutic interventions.

InChI:InChI=1/C12H13N3/c1-3-10(9-13-5-1)12-11-4-2-7-15(11)8-6-14-12/h1-5,7,9,12,14H,6,8H2

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 29709-35-1 1-(2-aminoethyl)pyrrole 

Downstream Products

• 1174283-09-0 N-(2-(2-(1-tert-butyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,4,6-tetramethylbenzenesulfonamide 
• 1174282-70-2 4-methoxy-N,2,3,6-tetramethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-11-4 N,2,4,6-tetramethyl-N-(2-(2-oxo-2-(1-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide 
• 1174282-63-3 N-(2-(2-(5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-2-oxoethoxy)ethyl)-N-isobutyl-4-methoxy-2,3,6-trimethylbenzenesulfonamide 
• 1174282-88-2 N-benzyl-4-methoxy-2,6-dimethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-17-0 N-(2-(2-(1-(3-fluorophenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,4,6-tetramethylbenzenesulfonamide 
• 1174282-82-6 N-benzyl-4-methoxy-2,3,6-trimethyl-N-(2-(2-(1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)benzenesulfonamide 
• 1174283-06-7 4-methoxy-N-(2-(2-(1-(3-methoxyphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-N,2,6-trimethylbenzenesulfonamide 
• 1174282-85-9 N-benzyl-N-(2-(2-(5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-2,3,6-trimethylbenzenesulfonamide 
• 1174282-72-4 N-(2-(2-(1-(6-chloropyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,3,6-tetramethylbenzenesulfonamide 
• 1174283-01-2 N-(2-(2-(1-(3,4-difluorophenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzenesulfonamide 
• 1174282-60-0 N-isobutyl-4-methoxy-2,3,6-trimethyl-N-(2-(2-oxo-2-(1-(pyridin-3-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethoxy)ethyl)benzenesulfonamide 
• 1174283-08-9 N-(2-(2-(1-(4-tert-butylphenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzenesulfonamide 
• 1174282-58-6 N-(2-(2-(6-((dimethylamino)methyl)-1-(thiophen-2-yl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-2-oxoethoxy)ethyl)-4-methoxy-N,2,6-trimethylbenzene-sulfonamide 

Relevant articles and documents

Substituted Sulfonamide Compounds

Substituted sulfonamide compounds corresponding to the formula I wherein m, n, p, Q, R1, R2, R3, R4, X, Y and Z have the respective meanings defined herein, pharmaceutical compositions containing such compounds, a process for their preparation, and the use of such compounds for the treatment and/or inhibition of pain and other conditions mediated by bradykinin receptor 1 (B1R) and/or bradykinin receptor 2 (B2R).