865722-96-9Relevant articles and documents
A short and efficient total synthesis of the bromotyrosine-derived alkaloid psammaplysene A
Xu, Jingjing,Wang, Kai,Wu, Jinlong
, p. 13747 - 13749 (2018/04/25)
Psammaplysene A, an inhibitor of FOXO1a-mediated nuclear export, has been synthesized by a concise and improved route from tyrosine-derived acid and amine fragments which were easily constructed using commercially available p-hydroxybenzaldehyde and tyramine as starting material, respectively. The strategy provides an efficient access of psammaplysene analogues that can be explored for potential pharmaceutical or biological activities.
Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export
Georgiades, Savvas N.,Clardy, Jon
, p. 4091 - 4094 (2007/10/03)
(Chemical Equation Presented) Two inhibitors of FOXO1a-mediated nuclear export, psammaplysenes A and B, have been synthesized by a flexible and efficient route. A common starting material, 4-iodophenol, was used to prepare both halves of these pseudosymme
