86630-46-8 Usage
Description
Nudol is a chemical compound belonging to the pyrophosphate family, specifically functioning as a Ca2+-dependent pyrophosphatase inhibitor. It is recognized for its capacity to inhibit the enzyme site of phosphate transfer and impede the hydrolysis of ATP to AMP and pyrophosphate. This inhibition leads to the accumulation of both substrates and end products, potentially disrupting cellular metabolism. Nudol plays a significant role in the study of cellular processes and holds promise for applications in pharmaceutical and biochemical research.
Uses
Used in Pharmaceutical Research:
Nudol is used as a research tool for understanding the role of pyrophosphatase enzymes in cellular metabolism and their potential as therapeutic targets. Its ability to inhibit these enzymes can provide insights into the development of new drugs targeting metabolic pathways.
Used in Biochemical Research:
In the field of biochemical research, Nudol is utilized as an inhibitor to study the effects of disrupted ATP hydrolysis on cellular processes. This can aid in the exploration of alternative energy sources and metabolic pathways within cells.
Used in Drug Development:
Nudol is employed as a lead compound in the development of new pharmaceuticals that target pyrophosphatase enzymes. Its inhibitory properties can be harnessed to create drugs that modulate cellular metabolism for the treatment of various diseases.
Used in Cellular Metabolism Studies:
In cellular metabolism studies, Nudol is used as an experimental agent to investigate the consequences of inhibiting key enzymes involved in energy production and transfer. This can contribute to a better understanding of cellular energy dynamics and the potential for metabolic intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 86630-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,6,3 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86630-46:
(7*8)+(6*6)+(5*6)+(4*3)+(3*0)+(2*4)+(1*6)=148
148 % 10 = 8
So 86630-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H14O4/c1-19-15-13(18)8-10-4-3-9-7-11(17)5-6-12(9)14(10)16(15)20-2/h3-8,17-18H,1-2H3
86630-46-8Relevant articles and documents
NUDOL, A PHENANTHRENE OF THE ORCHIDS EULOPHIA NUDA, ERIA CARINATA AND ERIA STRICTA
Bhandari, S. R.,Kapadi, A. H.,Mujumder, P. L.,Joardar, Mukta,Shoolery, J. N.
, p. 801 - 804 (2007/10/02)
Euolophia nuda; Eria carinata; Eria stricta; Orchidaceae; 2,7-dihydroxy-3,4-dimethoxyphenanthrene.An amorphous phenanthrene, named nudol has been isolated from Eulophia nuda, Eria carinata and E. stricta.It was identified as 2,7-dihydroxy-3,4-dimethoxyphenanthrene.Synthesis of nudol and its dimethyl ether is described.