86688-06-4Relevant articles and documents
Synthesis of New Axially Chiral Iodoarenes
Bekkaye, Mathieu,Masson, Géraldine
, p. 302 - 312 (2016)
A new family of axially chiral iodoarenes derived from commercially available (R)-1,1′-binaphthyl-2,2′-diamine have been synthesized and employed as catalysts in Kita's enantioselective oxidative spirolactonization of propanoic acid tethered 1-naphthol. Through this study, we explored the relationship between the hypervalent iodoarene geometry and enantioselectivity, contributing to the current understanding of axial-to-central chirality transfer in organoiodine(III) catalysis.
Hexafluoroisopropanol-Enabled Copper-Catalyzed Asymmetric Halogenation of Cyclic Diaryliodoniums for the Synthesis of Axially Chiral 2,2′-Dihalobiaryls
Ke, Jie,Zu, Bing,Guo, Yonghong,Li, Yingzi,He, Chuan
, p. 329 - 333 (2021/01/13)
An efficient asymmetric halogenation of cyclic diaryliodonium salts is demonstrated, which gives access to a wide range of axially chiral 2,2′-dihalobiaryls in good to excellent yields and with excellent enantioselectivities. The use of CuX with chiral bisoxazoline ligand and tetrabutylammonium halides in the unique solvent of hexafluoroisopropanol (HFIP) led to the best results in the process. The axially chiral 2,2′-dihalobiaryls can be transformed into a number of enantiopure chiral ligands that could be potentially useful in asymmetric catalysis.
Chiral binaphthalenes bearing two pyridine ligands attached via acetylene spacers. Synthesis and coordination study
Kasak, Peter,Brath, Henrich,Krascsenicsova-Polakova, Katarina,Kickova, Anna,Moldovan, Natalia,Putala, Martin
, p. 1139 - 1157 (2008/09/19)
An effective methodology has been developed for the synthesis of enantiopure 2,2′-dialkynylated 1,1′-binaphthalene derivatives. Enantiopure 2,2′-diiodo-1,1′-binaphthalene (10) provided 2,2′-diethynyl-1,1′-binaphthalene (16) in the Negishi alkynylation sup