868284-36-0 Usage
Description
1-BOC-AZEPANE-4-CARBOXYLIC ACID is a chemical compound that serves as a crucial reagent in the development of potent inhibitors for poly(ADP-ribose) polymerase (PARP). This enzyme plays a significant role in DNA repair and is often overactive in cancer cells, making it a key target for cancer treatment. 1-BOC-AZEPANE-4-CARBOXYLIC ACID's structure and properties allow it to be a valuable component in the synthesis of PARP inhibitors, which can potentially lead to the discovery of effective cancer therapies.
Uses
Used in Pharmaceutical Industry:
1-BOC-AZEPANE-4-CARBOXYLIC ACID is used as a reagent for the discovery of potent PARP inhibitors for the treatment of cancer. Its role in the synthesis of these inhibitors is vital, as it contributes to the development of drugs that can effectively target and suppress the activity of PARP enzymes in cancer cells. This, in turn, can lead to the inhibition of tumor growth and the enhancement of the effectiveness of other cancer treatments, such as chemotherapy and radiation therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 868284-36-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,2,8 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 868284-36:
(8*8)+(7*6)+(6*8)+(5*2)+(4*8)+(3*4)+(2*3)+(1*6)=220
220 % 10 = 0
So 868284-36-0 is a valid CAS Registry Number.
868284-36-0Relevant articles and documents
QUINUCLIDINONE ANALOGUES AS ANTICANCER AGENTS
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Page/Page column 85-86, (2021/08/13)
The disclosure includes compounds of Formula (I) and Formula(A) wherein R1, R2, R3, m, n, k, and L are defined herein. Also disclosed are methods for treating a neoplastic disease, autoimmune disease, or an inflammatory disorder with these compounds.
